Dra. Clara Bonanad Lozano

Investigadora Emergente
Grupo de Investigación Traslacional en Cardiopatía Isquémica

Presentación

Investigadora
Emergente
Dra. Clara Bonanad Lozano

clabolo@alumni.uv.es; clara.bonanad@uv.es

Publicaciones
Carbohydrate antigen 125-guided pre-TAVI medical optimization: impact on quality of life and clinical outcomes. Garcia-Blas S, Pernias V, Gonzalez D’gregorio J, Fernandez-Cisnal A, Bonanad C, Sastre C, Valero E, Minana G, Zaharia G, Nunez J, Sanchis J. Revista Espanola de Cardiologia (English ed.). 2024 Feb 2:S1885-5857(24)00037-9. doi: 10.1016/j.rec.2024.01.002. PMID: 38311024

Clinical benefit of bempedoic acid in randomized clinical trials. Cordero A, Olmo R, Santos-Gallego C, Fácila L, Bonanad C, Castellano J, Rodriguez-Mañero M, Seijas-Amigo J, González-Juanatey J, Badimon J. American Journal of Cardiology. 2023 Oct 15:205:321-324. doi: 10.1016/j.amjcard.2023.07.145. PMID: 37633067

Clinical predictors and prognosis of Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) without ST-Segment elevation in older adults. Gabaldon Perez A, Bonanad C, Garcia Blas S, Marcos Garces V, Gonzalez D’Gregorio J, Fernandez Cisnal A, Valero E, Minana G, Merenciano Gonzalez H, Mollar A, Bodi V, Nunez J, Sanchis J. Journal of Clinical Medicine. 2023 Feb 2;12(3):1181. doi: 10.3390/jcm12031181. PMID: 36769828

Consensus document on palliative care in cardiorenal patients. Bonanad C, Buades J, Leiva J, de la Espriella R, Marcos M, Núñez J, García-Llana H, Facila L, Sánchez R, Rodríguez-Osorio L, Alonso-Babarro A, Quiroga B, Berroteran D, Rodríguez C, Maidana D, Díez J. Frontiers in Cardiovascular Medicine. 2023 Dec 19:10:1225823. doi: 10.3389/fcvm.2023.1225823. PMID: 38179502

Extended use of dual antiplatelet therapy among older adults with acute coronary syndromes and associated variables: a cohort study. Ariza Sole A, Mateus Porta G, Formiga F, Garcia Blas S, Bonanad C, Nunez Gil I, Vergara Uzcategui C, Diez Villanueva P, Baneras J, Badia Molins C, Aboal J, Carreras-Mora J, Gabaldon Perez A, Parada Barcia J, Martinez Selles M, Comin Colet J, Raposeiras Roubin S. Thrombosis Journal. 2023 Mar 21;21(1):32. doi: 10.1186/s12959-023-00476-5. PMID: 36944967

Impact of persistent microvascular obstruction late after STEMI on AdverseLV remodeling: a CMR Study. Bodi V, Gavara J, Lopez-Lereu M, Monmeneu J, de Dios E, Perez-Sole N, Bonanad C, Marcos-Garces V, Canoves J, Minana G, Nunez J, Moratal D, Chorro F, Rodriguez-Palomares J, Freixa A, Borras R, Ortiz-Perez J, Rios-Navarro C. JACC. Cardiovascular Imaging. 2023 Jul;16(7):919-930. doi: 10.1016/j.jcmg.2023.01.021. PMID: 37052556

The efficacy of intensive lipid-lowering therapies on the reduction of LDLc and of major cardiovascular events. Cordero A, Olmo R, Badimon L, Santos-Gallego C, Castellano J, Fácila L, Rodriguez-Manero M, Bonanad C, Vilahur G, Escribano D, Badimon J, González-Juanatey J. Journal of Clinical Lipidology. 2023 Sep-Oct;17(5):602-611. doi: 10.1016/j.jacl.2023.08.006. PMID: 37775463

Validity of the minimum data set for outcomes research in patients hospitalized for heart failure in Spain. Bernal JL, Bonilla-Palomas JL, Rosillo N, Bonanad C, Elola J, Anguita M. Revista Espanola de Cardiologia (English ed.). 2023 Nov;76(11):938-939. doi: 10.1016/j.rec.2023.05.007. PMID: 37437880

Antithrombotic therapy in elderly patients with acute coronary síndromes. Bonanad C, Esteve-Claramunt F, Garcia-Blas S, Ayesta A, Diez-Villanueva P, Perez-Rivera J, Ferreiro J, Canoves J, Lopez-Fornas F, Sole A, Raposerias S, Vivas D, Blanco R, Berroteran D, Cordero A, Nunez J, Facila L, Nunez-Gil I, Gorriz J, Bodi V, Martinez-Selles M, Nodar J, Chorro F. Journal of Clinical Medicine. 2022 May 26;11(11):3008. doi: 10.3390/jcm11113008. PMID: 35683397

Applicability of echocardiographic strict negative criteria for suspected infective endocarditis. Marcos-Garces V, Gabaldon-Perez A, Merenciano-Gonzalez H, Soler M, Lorenzo-Hernandez M, Nunez-Marin G, de la Espriella R, Bonanad C, Nunez J, Chorro FJ, Bodi V, Santas E. American Journal of Cardiology. 2022 Jan 1;162:156-162. doi: 10.1016/j.amjcard.2021.09.012. PMID: 34728063

Bending oxygen saturation index and risk of worsening heart failure events in chronic heart failure. de la Espriella R, Amiguet M, Minana G, Rodriguez JC, Moyano P, Segarra D, Fernandez J, Santas E, Nunez G, Lorenzo M, Bonanad C, Alania E, Valle A, Sanchis J, Bodi V, Gorriz JL, Navarro J, Codina P, Voors AA, Bayes-Genis A, Nunez J. European Journal of Heart Failure. 2022 Nov;24(11):2108-2117. doi: 10.1002/ejhf.2651. PMID: 36054502

Cardiovascular prevention in elderly patients. Bonanad C, Fernandez-Olmo R, Garcia-Blas S, Alarcon J, Diez-Villanueva P, Mansilla C, Garcia-Pardo H, Toledo P, Ayesta A, Pereira E, Carol A, Castro-Conde A, de Pablo-Zarzoso C, Martinez-Selles M, Arrarte V, Campuzano R, Ariza-Sole A. Journal of Geriatric Cardiology. 2022 May 28;19(5):377-392. doi: 10.11909/j.issn.1671-5411.2022.05.004. PMID: 35722032

Combined assessment of stress cardiovascular magnetic resonance and angiography to predict the effect of revascularization in chronic coronary syndrome patients. Gavara J, Perez N, Marcos-Garces V, Monmeneu J, Lopez-Lereu M, Rios-Navarro C, de Dios E, Bonanad C, Canoves J, Moratal D, Palau P, Minana G, Nunez J, Chorro F, Bodi V. European Journal of Preventive Cardiology. 2022 Mar 11;29(2):407-416. doi: 10.1093/eurjpc/zwab170. PMID: 34686874

Comments on the 2021 ESC guidelines on cardiovascular disease prevention in clinical practice. Arrarte V, Campuzano R, Duque J, Aldama G, Barrios V, Bonanad C, Conde A, Olmo R, Gamez J, Guzman-Martinez G, Rey C, Vivas D, Avanzas P, Congost G, Boraita A, Bueno H, Calvo D, Delgado V, Dos L, Ferreira-Gonza-lez I, Doblas J, Figal D, Sambola A, Tejedor A, Ferreiro J, Alfonso F. Revista Espanola de Cardiologia. 2022 May;75(5):364-369. doi: 10.1016/j.rec.2021.10.023. PMID: 35165071

Ethical considerations in elderly patients with acute coronary syndrome. Ayesta A, Bonanad C, Diez-Villanueva P, Garcia-Blas S, Ariza-Sole A, Martinez-Selles M. Reviews in Cardiovascular Medicine. 2022 Feb 11;23(2):55. doi: 10.31083/j.rcm2302055. PMID: 35229546

Evaluation of the use of dual antiplatelet therapy beyond the first year after acute coronary syndrome. Bonanad C, Raposeiras-Roubin S, Garcia-Blas S, Nunez-Gil I, Vergara-Uzcategui C, Diez-Villanueva P, Baneras J, Molins C, Aboal J, Carreras J, Bodi V, Gabaldon-Perez A, Mateus-Porta G, Barcia J, Martinez-Selles M, Chorro F, Ariza-Sole A. Journal of Clinical Medicine. 2022 Mar 17;11(6):1680. doi: 10.3390/jcm11061680. PMID: 35330004

Exercise ECG Testing and stress cardiac magnetic resonance for risk prediction in patients with chronic coronary syndrome. Marcos-Garces V, Merenciano-Gonzalez H, Gabaldon-Perez A, Nunez-Marin G, Lorenzo-Hernandez M, Gavara J, Perez N, Rios-Navarro C, De Dios E, Bonanad C, Racugno P, Lopez-Lereu MP, Monmeneu JV, Chorro FJ, Bodi V. Journal of Cardiopulmonary Rehabilitation and Prevention. 2022 Jan 1;42(1):E7-E12. doi: 10.1097/HCR.0000000000000621. PMID: 34561369

Fragilidad y pronostico de los pacientes mayores con insuficiencia cardiaca. Jimenez-Mendez C, Diez-Villanueva P, Bonanad C, Ortiz-Cortes C, Barge-Caballero E, Goirigolzarri J, Esteban-Fernandez A, Perez-Rivera A, Cobo M, Lopez J, Sanz-Garcia A, Guerrero C, Pardo H, Robles C, Iglesias D, Manuel Garcia Pinilla J, Rodriguez L, Formiga F, Javier Martin-Sanchez F, Vidan M, Ariza A, Martinez-Selles M, Alfonso F. Revista Espanola de Cardiologia (english Ed.). 2022 Dec;75(12):1011-1019. doi: 10.1016/j.rec.2022.04.016. PMID: 35718066

Frailty and hospitalization burden in patients with chronic heart failure. Mollar A, Bonanad C, Diez-Villanueva P, Segarra D, Civera J, Sastre C, Conesa A, Villaescusa A, Fernández J, Miñana G, Navarro J, Sanchis J, Núñez J. American Journal of Cardiology. 2022 Nov 15;183:48-54. doi: 10.1016/j.amjcard.2022.08.013. PMID: 36153181

Magnetic resonance assessment of left ventricular ejection fraction at any time post-infarction for prediction of subsequent events in a large multicenter STEMI Registry. Gavara J, Marcos-Garces V, Lopez-Lereu, MP, Monmeneu JV, Rios-Navarro C, de Dios E, Perez N, Merenciano H, Gabaldon A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Nunez E, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Rodriguez-Palomares JF, Ortiz-Perez JT, Bodi V. Journal of Magnetic Resonance Imaging. 2022 Aug;56(2):476-487. doi: 10.1002/jmri.27789. PMID: 34137478

Oral anticoagulant use and appropriateness in elderly patients with atrial fibrillation in complex clinical conditions: ACONVENIENCE Study. Bonanad C, Formiga F, Anguita M, Petidier R, Gullon A. Journal of Clinical Medicine. 2022 Dec 14;11(24):7423. doi: 10.3390/jcm11247423. PMID: 36556039

Prognostic value of cardiac magnetic resonance early after ST-segment elevation myocardial infarction in older patients. Gabaldón-Pérez A, Marcos-Garcés V, Gavara J, López-Lereu MP, Monmeneu JV, Pérez N, Ríos-Navarro C, De Dios E, Merenciano-González H, Cànoves J, Racugno P, Bonanad C, Minana G, Núnez J, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Ortiz-Pérez JT, Rodríguez-Palomares JF, Bodí V. Age and Ageing. 2022 Nov 2;51(11):afac248. doi: 10.1093/ageing/afac248. PMID: 36436010

Residual ST-segment elevation to predict long-term clinical and CMR-derived outcomes in STEMI. Merenciano-Gonzalez H, Marcos-Garces V, Gavara J, Pedro-Tudela A, Lopez-Lereu M, Monmeneu J, Perez N, Rios-Navarro C, de Dios E, Gabaldon-Perez A, Albiach C, Racugno P, Bonanad C, Canoves J, Chorro F, Bodi V. Scientific Reports. 2022 Dec 17;12(1):21813. doi: 10.1038/s41598-022-26082-5. PMID: 36528716

Risk score for early risk prediction by cardiac magnetic resonance after acute myocardial infarction. Marcos-Garces V, Perez N, Gavara J, Lopez-Lereu MP, Monmeneu JV, Rios-Navarro C, de Dios E, Merenciano-Gonzalez H, Gabaldon-Perez A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Ortiz-Perez JT, Rodriguez-Palomares JF, Bodi V. International Journal of Cardiology. 2022 Feb 15;349:150-154. doi: 10.1016/j.ijcard.2021.11.050. PMID: 34826497

Second victims and quality of support resources among cardiology professionals. Baneras J, Jorge-Perez P, Bonanad C, Lopez Lluva M, Moll I, Fidel Kinori S. Revista Española de Cardiología (English ed.). 2022 Aug;75(8):686-688. doi: 10.1016/j.rec.2022.01.012. PMID: 35337779

Sex differences in the impact of frailty in elderly outpatients with heart failure. Diez-Villanueva P, Jimenez-Mendez C, Bonanad C, Ortiz-Cortes C, Barge-Caballero E, Goirigolzarri J, Esteban-Fernandez A, Perez-Rivera A, Cobo M, Sanz-Garcia A, Formiga F, Ariza-Sole A, Martinez-Selles M, Alfonso F. Frontiers In Cardiovascular Medicine. 2022 Sep 12;9:1000700. doi: 10.3389/fcvm.2022.1000700. PMID: 36172583

Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients. Pinana J, Vazquez L, Martino R, de la Camara R, Sureda A, Rodriguez-Veiga R, Garrido A, Sierra J, Ribera J, Torrent A, Mateos M, de la Rubia J, Tormo M, Diez-Campelo M, Garcia-Gutierrez V, Alvarez-Larran A, Sancho J, MartinGarcia-Sancho A, Yanez L, Simon J, Barba P, Abrisqueta P, Alvarez-Twose I, Bonanad S, Lecumberri R, Ruiz-Camps I, Navarro D, Hernandez-Rivas J, Cedillo A, Garcia-Sanz R, Bosch F. Leukemia & Lymphoma. 2022 Mar;63(3):538-550. doi: 10.1080/10428194.2021.1992619. PMID: 34668835

Stress cardiac magnetic resonance for mortality prediction and decision-making: registry of 2496 elderly patients with chronic coronary syndrome. Gabaldon-Perez A, Bonanad C, Garcia-Blas S, Gavara J, Rios-Navarro C, Perez-Sole N, de Dios E, Marcos-Garces V, Merenciano-Gonzalez H, Monmeneu J, Lopez-Lereu M, Nunez J, Chorro F, Bodi V. Revista Espanola de Cardiologia (english Ed.). 2022 Mar;75(3):223-231. doi: 10.1016/j.rec.2021.08.004. PMID: 34548244

Trade-off between the effects of embolic versus bleeding events on mortality in elderly patients with atrial fibrillation. Raposeiras-Roubin S, Abu-Assi E, Cespon Fernandez M, Blanco Prieto S, Barreiro Pardal C, Dominguez-Erquicia P, Melendo Viu M, Bonanad Lozano C, Rossello X, Ibanez B, Iniguez Romo A. Revista Espanola de Cardiologia (english Ed.). 2022 Apr;75(4):334-342. doi: 10.1016/j.rec.2021.02.003. PMID: 33839062

Venous leg compression for tissue decongestion in patients with worsening congestive heart failure. Civera J, Minana G, de la Espriella R, Santas E, Sastre C, Mollar A, Conesa A, Martinez A, Nunez E, Bayes-Genis A, Nunez J. Frontiers In Cardiovascular Medicine. 2022 Jul 8;9:847450. doi: 10.3389/fcvm.2022.847450. PMID: 35872894

Acute coronary syndrome in the older patient. Garcia-Blas S, Cordero A, Diez-Villanueva P, Martinez-Avial M, Ayesta A, Ariza-Sole A, Mateus-Porta G, Martinez-Selles M, Escribano D, Gabaldon-Perez A, Bodi V, Bonanad C. Journal of Clinical Medicine. 2021 Sep 14;10(18):4132. doi: 10.3390/jcm10184132. PMID: 34575243

CA125 but not NT-proBNP predicts the presence of a congestive intrarenal venous flow in patients with acute heart failure. Nunez-Marin G, de la Espriella R, Santas E, Lorenzo M, Minana G, Nunez E, Bodi V, Gonzalez M, Gorriz J, Bonanad C, Sanchis J, Bayes-Genis A, Nunez J. European Heart Journal-Acute Cardiovascular Care. 2021 Jun 30;10(5):475-483. doi: 10.1093/ehjacc/zuab022. PMID: 33829233

Direct oral anticoagulants versus warfarin in octogenarians with nonvalvular atrial fibrillation: a systematic review and meta-analysis. Bonanad C, Garcia-Blas S, Torres Llergo J, Fernandez-Olmo R, Diez-Villanueva P, Ariza-Sole A, Martinez-Selles M, Raposeiras S, Ayesta A, Bertomeu-Gonzalez V, Tarazona Santabalbina F, Facila L, Vivas D, Gabaldon-Perez A, Bodi V, Nunez J, Cordero A. Journal of Clinical Medicine. 2021 Nov 12;10(22):5268. doi: 10.3390/jcm10225268. PMID: 34830548

Frailty scales for prognosis assessment of older adult patients after acute myocardial infarction. Garcia-Blas S, Bonanad C, Fernandez-Cisnal A, Sastre-Arbona C, Ruescas-Nicolau M, D’Gregorio J, Valero E, Minana G, Palau P, Tarazona-Santabalbina F, Ros V, Nunez J, Sanchis J. Journal of Clinical Medicine. 2021 Sep 21;10(18):4278. doi: 10.3390/jcm10184278. PMID: 34575389

Long-term outcome of patients with NSTEMI and nonobstructive coronary arteries by different angiographic subtypes. Garcia-Blas S, Gonzalez D’ Gregorio J, Bonanad C, Fernandez-Cisnal A, Valero E, Minana G, Mollar A, Nunez J, Sanchis J. Revista Espanola de Cardiologia. 2021 Nov;74(11):919-926. doi: 10.1016/j.rec.2020.10.008. PMID: 33349589

Long-Term Prognostic Value of Cognitive Impairment on Top of Frailty in Older Adults after Acute Coronary Syndrome. Sanchis J, Bonanad C, Garcia-Blas S, Ruiz V, Fernandez-Cisnal A, Sastre C, Ruescas A, Valero E, Gonzalez J, Mollar A, Minana G, Nunez J. Journal of Clinical Medicine. 2021 Jan 24;10(3):444. doi: 10.3390/jcm10030444. PMID: 33498816

Longitudinal strain in remote non-infarcted myocardium by tissue tracking CMR: characterization, dynamics, structural and prognostic implications. GAVARA DOÑATE J, Rodriguez-Palomares J, Rios Navarro C, Valente F, Monmeneu J, Lopez-Lereu M, Ferreira-Gonzalez I, Garcia Del Blanco B, Otaegui I, Canoves Femenia J, De Dios Lluch E, Pérez Solé N, Racugno P, Bonanad Lozano C, Miñana Escriva G, Marcos Garcés V, Barrabes J, Evangelista A, Moratal D, Bayes-Genis A, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. The International Journal Of Cardiovascular Imaging. 2021 Jan;37(1):241-253. doi: 10.1007/s10554-020-01890-w. PMID: 32488452

Main challenges of electrolyte imbalance in older patients with coronavirus disease and risk of QT prolongation. Response. Bonanad C, Diez-Villanueva P, Garcia-Blas S, Martinez-Selles M. Revista Espanola de Cardiologia. 2021 Feb;74(2):199-200. doi: 10.1016/j.recesp.2020.08.014. PMID: 32982010

Randomized Comparison of Exercise Intervention Versus Usual Care in Older Adult Patients with Frailty After Acute Myocardial Infarction. Sanchis J, Sastre C, Ruescas A, Ruiz V, Valero E, Bonanad C, Garcia-Blas S, Fernandez-Cisnal A, Gonzalez J, Minana G, Nunez J. American Journal of Medicine. 2021 Mar;134(3):383-390.e2. doi: 10.1016/j.amjmed.2020.09.019. PMID: 33228950

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

sST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction. De La Espriella Juan R, Bayes-Genis A, Revuelta E, Miñana Escriva G, Santas Olmeda E, Llacer P, Garcia Blas S, Fernández Cisnal A, Bonanad Lozano C, Ventura S, Sanchez R, Bodí Peris V, Cordero A, Facila De La Esperanza R, Mollar Fernandez A, Sanchis Fores J, Improve-Hf Investigators, Nuñez Villota J. Journal Of Cardiac Failure. 2021 Apr;27(4):427-434. doi: 10.1016/j.cardfail.2020.10.002. PMID: 33038531

Telematic cardiology consultation in the elderly. The 5M framework can help. Diez-Villanueva P, Bonanad C, Ariza-Sole A, Martinez-Selles M. Revista Espanola de Cardiologia. 2021 Jan;74(1):116-117. doi: 10.1016/j.recesp.2020.08.024. PMID: 32994661

Proyectos
Referencia: SEC/FEC-INV-CLI 21/024
Título: Resonancia magnética cardíaca de estrés con vasodilatadores para predecir la mortalidad a largo plazo en un amplio registro retrospectivo de pacientes con cardiopatía isquémica conocida o sospechada
Entidad Financiadora: Sociedad Española de Cardiología
Investigador principal: Vicent Bodí Peris
Duración: 2021 – 2022
Presupuesto: 15.000 €
Referencia: PI20/00637
Título: Resolución de la obstrucción microvascular tras un infartodemiocardio: evaluación de las consecuencias estructurales y clínicas y búsqueda de nuevas opciones terapéuticas
Entidad Financiadora: Instituto de Salud Carlos III – Cofinanciado FEDER
Investigador principal: Vicent Bodí Peris, Clara Bonanad Lozano
Duración: 2021 – 2023
Presupuesto: 129.470 €
Referencia: GV/2018/116
Título: Estudio multidisciplinar de la dinámica, mecanismos básicos, diagnóstico y exploración de nuevas oportunidades terapéuticas en la obstrucción microvascular tras infarto agudo de miocardio
Entidad Financiadora: Conselleria de Educación, Cultura y Deporte
Investigador principal: Clara Bonanad Lozano
Duración: 2018 – 2019
Presupuesto: 15.000 €