Research Group on Pedriatric Nutrition

Cardiovascular Area

Cardiovascular area:

– Study of metabolome and microbiome in obese children with/without insulin resistance before and after personalized nutritional intervention and physical exercise

Area of human milk:

– Characterization of mother-infant microbiome in term and preterm infants. Influence of perinatal variables

Area of hospital malnutrition and artificial nutrition:

– Validation of the pediatric screening tools for detecting the risk of malnutrition linked to chronic disease and pediatric hospitalization

Coordinatora
Dra. Cecilia Martínez Costa
cecilia.martinez@uv.es; cmcosta@uv.es

RESEARCHERS
Leading, R4

Cecilia Martínez Costa    
Javier Buesa Gómez

Established, R3

Elena Crehuá Gaudiza
Francisco Núñez Gómez
Javier Estañ Capell
Jose Vicente Arcos Machancoses
Laura Martínez Rodríguez

Recognised/Emerging, R2

Ana Paula Grattarola
Jose Luis López Prats
Patricia Roselló Millet

First Stage, R1

Alba Peretó Moll
Ana Barrés Fernández
Ángel Vicente Valls Arévalo
Isidro Robredo García
Laura Núñez Martínez
Vicente Posadas Blázquez

STAFF
Collaborating Researchers

Inmaculada Tarazona Casany

Nurse
Technicians
Administrative assistant
Publications
Assessment of SARS-CoV-2 neutralizing antibody titers in breastmilk from convalescent and vaccinated mothers. Bauerl C, Zulaica J, Rusu L, Moreno A, Perez-Cano F, Lerin C, Mena-Tudela D, Aguilar-Camprubi L, Parra-Llorca A, Martinez-Costa C, Geller R, Collado M. Iscience. 2023 Jun 16;26(6):106802. doi: 10.1016/j.isci.2023.106802. PMID: 37197591

Benefits of paediatric to adult transition programme in inflammatory bowel disease: the BUTTERFLY Study of GETECCU and SEGHNP. De Célix C, Martín-de-Carpi J, Pujol-Muncunill G, Palomino L, Rodríguez-Belvís M, Martín-Masot R, Navas-López V, Ricart E, Casanova M, Rodríguez-Martínez A, Leo-Carnerero E, Alcaraz A, Mañosa M, Hernández V, Cobelas M, Sánchez C, Menchén L, Mesonero F, Barreiro-De Acosta M, Martinón-Torres N, Sandoval C, Váazquez A, Corsino P, Vicente R, Hernández-Camba A, Alonso J, Alonso-Abreu I, Millán A, Reverter L, Castro B, Fernández-Salgado E, Cuiñas M, Benítez J, Madero L, Clemente F, Riestra S, Jiménez-Treviño S, Boscá-Watts M, Crehuáa-Gaudiza E, Moya M, Huguet J, Largo-Blanco E, Vives L, Plaza R, Guerra I, Barrio J, Escartín L, Alfambra E, Cruz N, Muñoz M, Pino M, Van Domselaar M, Botella B, Miquel D, Grau M, De La Mano A, Ber Y, Iñiguez M, Martínez-Pérez T, Chaparro M, Gisbert J. Journal of Clinical Medicine. 2023 Jul 21;12(14):4813. doi: 10.3390/jcm12144813. PMID: 37510928

Breast milk immune composition varies during the transition stage of lactation: characterization of immunotypes in the MAMI cohort. Rio-Aige K, Fernández-Bargalló A, Vegas-Lozano E, Miñarro-Alonso A, Castell M, Selma-Royo M, Martínez-Costa C, Rodríguez-Lagunas M, Collado M, Pérez-Cano F. Frontiers in Nutrition. 2023 Nov 23:10:1252815. doi: 10.3389/fnut.2023.1252815. PMID: 38075221

Culture of human rotaviruses in relevant models shows differences in culture-adapted and nonculture-adapted strains. Peña-Gil N, Randazzo W, Carmona-Vicente N, Santiso-Bellón C, Carcamo-Cálvo R, Navarro-Lleó N, Monedero V, Yebra M, Buesa J, Gozalbo-Rovira R, Rodríguez-Díaz J. International Journal of Molecular Sciences. 2023 Dec 11;24(24):17362. doi: 10.3390/ijms242417362. PMID: 38139191

Differences when classifying small for gestational age preterm infants according to the growth chart applied. Estan Capell J, Alarcon Torres B, Miro Pedro M, Martinez Costa C. American Journal of Perinatology. 2023 Jan 29. doi: 10.1055/s-0043-1761297. PMID: 36709759

Distinct breast milk microbiota, cytokine, and adipokine profiles are associated with infant growth at 12 months: an in vitro host-microbe interaction mechanistic approach. Cortes-Macias E, Selma-Royo M, Rio-Aige K, Bauerl C, Rodriguez-Lagunas M, Martinez-Costa C, Perez-Cano F, Collado M. Food & Function. 2023 Jan 3;14(1):148-159. doi: 10.1039/d2fo02060b. PMID: 36472137

Effects of infant feeding with goat milk formula or cow milk formula on atopic dermatitis: protocol of the randomised controlled Goat Infant Formula Feeding and Eczema (GIraFFE) trial. Ferry JM, Galera-Martínez R, Campoy C, Sáenz de Pipaón M, Jarocka-Cyrta E, Walkowiak J, Romanczuk B, Escribano J, Gispert M, Grattarola P, Gruszfeld D, Iglesia I, Grote V, Demmelmair H, Handel U, Gallier S, Koletzko B. BMJ Open. 2023 Apr 13;13(4):e070533. doi: 10.1136/bmjopen-2022-070533. PMID: 37055203

Efficacy and effectiveness of influenza vaccination in healthy children. A review of current evidence. Orrico-Sanchez A, Valls-Arevalo A, Garces-Sanchez M, Alvarez Aldean J, Ortiz de Lejarazu Leonardo R. Enfermedades Infecciosas y Microbiologia Clinica (english Ed.). 2023 Aug-Sep;41(7):396-406. doi: 10.1016/j.eimce.2022.02.016. PMID: 36681572

Geographical distribution of risk genotypes in pediatric patients with celiac disease in Spain. Sanchez Valverde F, Martinez Ojinaga E, Donat E, Bodas A, Bandres E, Torres R, Ibanez B, Cilleruelo M, Castillejo G, Perez Solis D, Ochoa C, Eizaguirre F, Garcia S, Garcia J, Barrio J, Vecino R, Miranda M, Juste M, Salazar J, Armas H, Ortigosa L, Urruzuno P, Garcia Z, Balmaseda E, Martinez C, La Orden E, Codoner P, Roca A, Trillo C, Sebastian M, Garcia R, Pena-Quintana L, Barros P, Soria M, Garcia R, Perez-Moneo B, Polanco I, Ribes C, Roman E. Human Immunology. 2023 Apr;84(4):290-295. doi: 10.1016/j.humimm.2023.01.010. PMID: 36858916

Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and growth. Yeruva L, Mulakala B, Rajasundaram D, Gonzalez S, Cabrera-Rubio R, Martínez-Costa C, Collado M. Clinical Nutrition. 2023 Dec;42(12):2528-2539. doi: 10.1016/j.clnu.2023.10.011. PMID: 37931372

Is there an adequate therapeutic approach to thyroid pathology in patients with Down Syndrome?. Murillo-Llorente M, Pérez-Bermejo M, Llacer-Heredia V, Tomás-Aguirre B, Valls-Arévalo A, Tomás-Aguirre F. Diagnostics. 2023 Nov 21;13(23):3499. doi: 10.3390/diagnostics13233499. PMID: 38066740

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and lateral flow immunochromatography for rapid identification of beta-lactamase-gene-harboring Enterobacterales in urine specimens: Performance and cost-benefit analyses. Sánchez D, Torres I, Padrón C, Giménez E, Colomina J, Carretero D, Buesa J, Navarro D, Albert E. Diagnostic Microbiology and Infectious Disease. 2023 Oct 30;108(2):116127. doi: 10.1016/j.diagmicrobio.2023.116127. PMID: 37988931

Safety and efficacy of a new supplementation protocol in patients with cystic fibrosis and vitamin D deficiency. Mangas Sanchez C, Garriga Garcia M, Serrano Nieto M, Garcia Romero R, Alvarez Beltran M, Crehua Gaudiza E, Vicente Santamaria S, Martinez Costa C, Diaz Martin J, Bousono Garcia C, Gonzalez Jimenez D. Anales de Pediatria. 2023 Apr;98(4):257-266. doi: 10.1016/j.anpede.2023.02.015. PMID: 36932016

Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study. Selma-Royo M, Bauerl C, Mena-Tudela D, Aguilar-Camprubi L, Perez-Cano FJ, Parra-Llorca A, Lerin C, Martinez-Costa C, Collado MC. Genome Medicine. 2022 Apr 21;14(1):42. doi: 10.1186/s13073-022-01043-9. PMID: 35449030

BD MAX enteric bacterial, bacterial plus, and virus panels for diagnosis of acute infectious gastroenteritis: a cost-benefit analysis. Ferrer J, Gimenez E, Carretero D, Buesa J, Morillas F, Granell R, Fuenmayor A, Navarro D, Albert E. Microbiology Spectrum. 2022 Oct 26;10(5):e0088022. doi: 10.1128/spectrum.00880-22. PMID: 36069590

Breast milk lipidome is associated with maternal diet and infants’ growth. Calvo-Lerma J, Selma-Royo M, Hervas D, Yang B, Intonen L, Gonzalez S, Martinez-Costa C, Linderborg K, Collado M. Frontiers in Nutrition. 2022 Jul 6;9:854786. doi: 10.3389/fnut.2022.854786. PMID: 35873422

Correlation of anti-tissue transglutaminase antibodies with the mucosal changes and IgA status of children with celiac disease. Donat E, Roca M, Castillejo G, Sanchez-Valverde F, Garcia-Burriel JI, Martinez-Ojinaga E, Eizaguirre FJ, Barrio J, Cilleruelo ML, Perez-Solis D, Ochoa-Sangrador C, Vecino-Lopez R, Miranda-Cid MC, Garcia-Calatayud S, Torres-Peral R, Juste M, Armas H, Barros-Garcia P, Leis R, Solaguren R, Salazar JC, Garcia-Romero R, Ortigosa L, Pena-Quintana L, Urruzuno P, Codoner P, Garcia-Casales Z, Masiques ML, Galicia-Poblet G, Crehua-Gaudiza E, Balmaseda E, Rubio-Santiago J, Polanco-Allue I, Roman-Riechmann E, Ribes-Koninck C. Journal of Pediatric Gastroenterology and Nutrition. 2022 Dec 1;75(6):743-748. doi: 10.1097/MPG.0000000000003620. PMID: 36123770

Cross-cultural adaptation to Spanish and content validity of three nutritional risk scales. Balaguer Lopez E, Garcia-Molina P, Nunez F, Crehua-Gaudiza E, Montal Navarro M, Pedron Giner C, Vitoria Minana I, Jovani Casano C, Galera Martinez R, Gomez-Lopez L, Rodriguez Martinez G, Martinez-Costa C. Anales de Pediatria. 2022 Jul;97(1):12-21. doi: 10.1016/j.anpede.2022.06.001. PMID: 35729061

Galectins-1,-3 and-9 are present in breast milk and have a role in early life development. Rio-Aige K, Girbal M, Selma-Royo M, Parra-Llorca A, Gonzalez S, Martinez-Costa C, Castell M, Collado M, Perez-Cano F, Rodriguez-Lagunas M. Nutrients. 2022 Oct 17;14(20):4338. doi: 10.3390/nu14204338. PMID: 36297023

Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe. Giuffrida F, Fleith M, Goyer A, Samuel T, Elmelegy-Masserey I, Fontannaz P, Cruz-Hernandez C, Thakkar S, Monnard C, De Castro C, Lavalle L, Rakza T, Agosti M, Al-Jashi I, Pereira A, Costeira M, Marchini G, Vanpee M, Stiris T, Stoicescu S, Silva M, Picaud J, Martinez-Costa C, Domellof M, Billeaud C. European Journal of Nutrition. 2022 Jun;61(4):2167-2182. doi: 10.1007/s00394-021-02788-6. PMID: 35072787

Maternal diet is associated with human milk oligosaccharide profile. Selma-Royo M, Gonzalez S, Gueimonde M, Chang M, Furst A, Martinez-Costa C, Bode L, Collado M. Molecular Nutrition & Food Research. 2022 Aug;66(15):e2200058. doi: 10.1002/mnfr.202200058. PMID: 35612565

Metallomic and untargeted metabolomic signatures of human milk from SARS-CoV-2 Positive mothers. Arias-Borrego A, Soto Cruz FJ, Selma-Royo M, Bäuerl C, García Verdevio E, Pérez-Cano FJ, Lerin C, Velasco López I, Martínez-Costa C, Collado MC, García-Barrera T. Molecular Nutrition & Food Research. 2022 Aug;66(16):e2200071. doi: 10.1002/mnfr.202200071. PMID: 35687731

Mode of neonatal delivery influences the nutrient composition of human milk: results from a multicenter european cohort of lactating women. Samuel T, Thielecke F, Lavalle L, Chen C, Fogel P, Giuffrida F, Dubascoux S, Martinez-Costa C, Haaland K, Marchini G, Agosti M, Rakza T, Costeira M, Picaud J, Billeaud C, Thakkar S. Frontiers in Nutrition. 2022 Apr 6;9:834394. doi: 10.3389/fnut.2022.834394. PMID: 35464009

Persistence of Anti SARS-CoV-2 antibodies in breast milk from infected and vaccinated women after in vitro-simulated gastrointestinal digestion. Calvo-Lerma J, Bueno-Llamoga P, Bauerl C, Cortes-Macias E, Selma-Royo M, Perez-Cano F, Lerin C, Martinez-Costa C, Collado M. Nutrients. 2022 May 19;14(10):2117. doi: 10.3390/nu14102117. PMID: 35631258

Recombinant noroviruses circulating in Spain from 2016 to 2020 and proposal of two novel genotypes within genogroup I. Navarro-Lleó N, Santiso-Bellón C, Vila-Vicent S, Carmona-Vicente N, Gozalbo-Rovira R, Cárcamo-Calvo R, Rodríguez-Díaz J, Buesa J. Microbiology Spectrum. 2022 Aug 31;10(4):e0250521. doi: 10.1128/spectrum.02505-21. PMID: 35862999

Replication of human norovirus in mice after antibiotic-mediated intestinal bacteria depletion. Santiso-Bellon C, Gozalbo-Rovira R, Buesa J, Rubio-Del-Campo A, Pena-Gil N, Navarro-Lleo N, Carcamo-Calvo R, Yebra MJ, Monedero V, Rodriguez-Diaz J. International Journal of Molecular Sciences. 2022 Sep 13;23(18):10643. doi: 10.3390/ijms231810643. PMID: 36142552

RNA viral loads of SARS-CoV-2 Alpha and Delta variants in nasopharyngeal specimens at diagnosis stratified by age, clinical presentation and vaccination status. Costa R, Olea B, Bracho M, Albert E, de Michelena P, Martinez-Costa C, Gonzalez-Candelas F, Navarro D. Journal of Infection. 2022 Apr;84(4):579-613. doi: 10.1016/j.jinf.2021.12.018. PMID: 34953901

SARS-CoV-2 RNA and antibody detection in breast milk from a prospective multicentre study in Spain. Bauerl C, Randazzo W, Sanchez G, Selma-Royo M, Garcia-Verdevio E, Martinez L, Parra-Llorca A, Lerin C, Fumado V, Crovetto F, Crispi F, Perez-Cano F, Rodriguez G, Ruiz-Redondo G, Campoy C, Martinez-Costa C, Collado M, MilkCORONA study team. Archives of Disease in Childhood. Fetal and Neonatal Edition. 2022 Mar;107(2):216-221. doi: 10.1136/archdischild-2021-322463. PMID: 34417223

Spanish National Registry of paediatric coeliac disease: changes in the clinical presentation in the 21st century. Solis D, Pascual M, Sangrador C, Burriel J, Visus F, Arocena F, Calatayud S, Nodal E, Aliaga E, Torres J, de Villasante G, Cid M, Peral R, Lopez R, Ruiz M, Ramos H, Garcia P, Leis R, Alberdi R, Quero J, Romero R, del Clastillo L, Quintana L, Telleria P, Franch P, Casales Z, Mas M, Poblet G, Costa C, Serrano E, Allue I, Koninck C, Riechmann E. Journal of Pediatric Gastroenterology and Nutrition. 2022 Jun 1;74(6):805-811. doi: 10.1097/MPG.0000000000003424. PMID: 35192578

The dietary inflammatory index is associated with subclinical mastitis in lactating European women. Afeiche M, Iroz A, Thielecke F, De Castro A, Lefebvre G, Draper C, Martinez-Costa C, Haaland K, Marchini G, Agosti M, Domellof M, Rakza T, Costeira M, Vanpee M, Billeaud C, Picaud J, Hian D, Liu G, Shivappa N, Hebert J, Samuel T. Nutrients. 2022 Nov 8;14(22):4719. doi: 10.3390/nu14224719. PMID: 36432405

Adaptive immune responses to SARS-CoV-2 in recovered severe COVID-19 patients. Olea B, Albert E, Torres I, Amat P, Remigia M, Gozalbo-Rovira R, Rodriguez-Diaz J, Buesa J, Blasco M, Redon J, Signes-Costa J, Navarro D. Journal of Clinical Virology. 2021 Sep;142:104943. doi: 10.1016/j.jcv.2021.104943. PMID: 34391981

Amplification of human beta-glucoronidase gene for appraising the accuracy of negative SARS-CoV-2 RT-PCR results in upper respiratory tract specimens. Albert Vicent E, Ferrer Lores B, Torres Fink I, Serrano Alcalá A, Alcaráz Soriana M, Buesa Gomez J, Solano Vercet C, Colomina Rodríguez F, Bueno Ferrando F, Huntley Pascual D, Olea Miguel B, Valdivia Piqueres A, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):48-50. doi: 10.1002/jmv.26112. PMID: 32484950

An investigation of the potential association between gastrointestinal viral and bacterial infection and development of intestinal acute graft versus host disease following allogeneic hematopoietic stem cell transplantation. Bueno F, Albert E, Gimenez E, Pinana J, Perez A, Gomez M, Hernandez-Boluda J, Gonzalez-Barbera E, Montoro J, Buesa J, Guerreiro M, Balaguer-Rosello A, Hernani R, Sanz J, Solano C, Navarro D. Journal of Medical Virology. 2021 Aug;93(8):4773-4779. doi: 10.1002/jmv.26892. PMID: 33605457

Breastfeeding practices influence the breast milk microbiota depending on pre-gestational maternal bmi and weight gain over pregnancy. Cortes-Macias E, Selma-Royo M, Martinez-Costa C, Collado MC. Nutrients. 2021 Apr 30;13(5):1518. doi: 10.3390/nu13051518. PMID: 33946343

Case report: primary peritonitis as the onset of pediatric Menetrier’s disease. Barres-Fernandez A, Piolatti-Luna A, Breton-Martinez J, Crehua-Gaudiza E, Quinones-Torrelo C, Moscardo-Navarro A, Fuertes-Latasa C, Martinez-Costa C. Frontiers in Pediatrics. 2021 Jan 13;8:589853. doi: 10.3389/fped.2020.589853. PMID: 33520889

Diagnosis of celiac disease in clinical practice: present and future. Crehua-Gaudiza E, Barres Fernandez A, Jovani Casano C, Latorre Tejerina M, Largo Blanco E, Moreno Ruiz M, Berghezan Suarez A, Garcia-Peris M, Gil Piquer R, Coret Sinisterra A, Martinez-Barona S, Salido-Capilla C, Requena Fernandez M, Arcos-Machancoses J, Martinez-Costa C. Anales de Pediatria. 2021 Apr;94(4):223-229. doi: 10.1016/j.anpedi.2020.07.008. PMID: 32891578

Effect of lockdown on the preterm births in a Valencian Comunity. Molina-Merino A, Martinez-Rodriguez L, Cubells-Garcia E, Hortelano-Platero V, Estan-Capell J. Anales de Pediatria. 2021 Nov;95(5):379-381. doi: 10.1016/j.anpede.2021.07.004. PMID: 34697000

Epidemiological and Genetic Characterization of Sapovirus in Patients with Acute Gastroenteritis in Valencia (Spain). de Oliveira-Tozetto S, Santiso-Bellon C, Ferrer-Chirivella J, Navarro-Lleo N, Vila-Vicent S, Rodriguez-Diaz J, Buesa J. Viruses. 2021 Jan 26;13(2):184. doi: 10.3390/v13020184. PMID: 33530573

Evaluation of a rapid antigen detection test (Panbio (TM) COVID-19 Ag Rapid Test Device) as a point-of-care diagnostic tool for COVID-19 in a pediatric emergency department. Carbonell-Sahuquillo S, Lazaro-Carreno M, Camacho J, Barres-Fernandez A, Albert E, Torres I, Breton-Martinez J, Martinez-Costa C, Navarro D. Journal of Medical Virology. 2021 Dec;93(12):6803-6807. doi: 10.1002/jmv.27220. PMID: 34289136

Global trends in norovirus genotype distribution among children with acute gastroenteritis. Cannon J, Bonifacio J, Bucardo F, Buesa J, Bruggink L, Chan M, Fumian T, Giri S, Gonzalez M, Hewitt J, Lin J, Mans J, Munoz C, Pan C, Pang X, Pietsch C, Rahman M, Sakon N, Selvarangan R, Browne H, Barclay L, Vinje J. Emerging Infectious Diseases. 2021 May;27(5):1438-1445. doi: 10.3201/eid2705.204756. PMID: 33900173

Hepatitis C and beta-thalassemia major in children: experience with glecaprevir/pibrentasvir. Quintero García D, Sebastián Cuevas F, Crehuá Gaudiza E. Revista Espanola de Enfermedades Digestivas. 2021 Feb;113(2):150-151. doi: 10.17235/reed.2020.7092/2020. PMID: 33207896

Home and Ambulatory Artificial Nutrition (NADYA) Group report: home parenteral nutrition in Spain, 2019. Wanden-Berghe C, Virgili Casas N, Cuerda Compes C, et al. Nutricion Hospitalaria. 2021 Dec 9;38(6):1304-1309. doi: 10.20960/nh.03720. PMID: 34670394

Human milk oligosaccharides, infant growth, and adiposity over the first 4 months of lactation. Binia A, Lavalle L, Chen C, Austin S, Agosti M, Al-Jashi I, Pereira A, Costeira M, Silva M, Marchini G, Martinez-Costa C, Stiris T, Stoicescu S, Vanpee M, Rakza T, Billeaud C, Picaud J, Domellof M, Adams R, Castaneda-Gutierrez E, Sprenger N. Pediatric Research. 2021 Sep;90(3):684-693. doi: 10.1038/s41390-020-01328-y. PMID: 33446921

Inference of SARS-CoV-2 spike-binding neutralizing antibody titers in sera from hospitalized COVID-19 patients by using commercial enzyme and chemiluminescent immunoassays. Valdivia A, Torres I, Latorre V, Frances-Gomez C, Albert E, Gozalbo-Rovira R, Alcaraz M, Buesa J, Rodriguez-Diaz J, Geller R, Navarro D. European Journal of Clinical Microbiology & Infectious Diseases. 2021 Mar;40(3):485-494. doi: 10.1007/s10096-020-04128-8. PMID: 33404891

Initial viral load and decay kinetics of SARS-CoV-2 lineage B.1.1.7 in the upper respiratory tract of adults and children. Costa R, Bueno F, Gimenez E, Bracho A, Albert E, Carretero D, de Michelena P, Martinez-Costa C, Gonzalez-Candelas F, Navarro D. Journal of Infection. 2021 Oct;83(4):496-522. doi: 10.1016/j.jinf.2021.08.015. PMID: 34390756

Interaction of Intestinal Bacteria with Human Rotavirus during Infection in Children. Gozalbo-Rovira R, Rubio-Del-Campo A, Santiso-Bellon C, Vila-Vicent S, Buesa J, Delgado S, Molinero N, Margolles A, Yebra M, Collado M, Monedero V, Rodriguez-Diaz J. International Journal of Molecular Sciences. 2021 Jan 20;22(3):1010. doi: 10.3390/ijms22031010. PMID: 33498321

Levels of predominant intestinal microorganisms in 1 month-old full-term babies and weight gain during the first year of life. Gonzalez S, Selma-Royo M, Arboleya S, Martinez-Costa C, Solis G, Suarez M, Fernandez N, de los Reyes-Gavilan C, Diaz-Coto S, Martinez-Camblor P, Collado M, Gueimonde M. Nutrients. 2021 Jul 14;13(7):2412. doi: 10.3390/nu13072412. PMID: 34371922

Maternal diet during pregnancy and intestinal markers are associated with early gut microbiota. Selma-Royo M, García Mantrana I, Calatayud M, Parra-Llorca A, Martinez Costa C, Collado M. European Journal Of Nutrition. 2021 Apr;60(3):1429-1442. doi: 10.1007/s00394-020-02337-7. PMID: 32728880

Maternal Diet Shapes the Breast Milk Microbiota Composition and Diversity: Impact of Mode of Delivery and Antibiotic Exposure. Cortes-Macias E, Selma-Royo M, Garcia-Mantrana I, Calatayud M, Gonzalez S, Martinez-Costa C, Collado M. Journal of Nutrition. 2021 Feb 1;151(2):330-340. doi: 10.1093/jn/nxaa310. PMID: 33188413

Microbiota depletion promotes human rotavirus replication in an adult mouse model. Gozalbo-Rovira R, Santiso-Bellon C, Buesa J, Rubio-del-Campo A, Vila-Vicent S, Munoz C, Yebra M, Monedero V, Rodriguez-Diaz J. Biomedicines. 2021 Jul 20;9(7):846. doi: 10.3390/biomedicines9070846. PMID: 34356911

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure. Lopez-Labrador F, Brown J, Fischer N, Harvala H, Van Boheemen S, Cinek O, Sayiner A, Madsen T, Auvinen E, Kufner V, Huber M, Rodriguez C, Jonges M, Honemann M, Susi P, Sousa H, Klapper P, Perez-Cataluna A, Hernandez M, Molenkamp R, der Hoek L, Schuurman R, Couto N, Leuzinger K, Simmonds P, Beer M, Hoper D, Kamminga S, Feltkamp M, Rodriguez-Diaz J, Keyaerts E, Nielsen X, Puchhammer-Stockl E, Kroes A, Buesa J, Breuer J, Claas E, de Vries J, ESCV Network on Next-Generation Sequencing. Journal of Clinical Virology. 2021 Jan;134:104691. doi: 10.1016/j.jcv.2020.104691. PMID: 33278791

Sjogren-Larsson syndrome in Spain: description of three new cases. Villar-Vera C, Cuesta Peredo A, Monfort-Belenguer L, Abellan Sanchez M, Martinez-Costa C. Anales de Pediatria. 2021 Sep;95(3):203-204. doi: 10.1016/j.anpede.2020.07.019. PMID: 34340960

Suitability of Two Rapid Lateral Flow Immunochromatographic Assays for Predicting SARS-CoV-2 Neutralizing Activity of Sera. Valdivia A, Torres I, Latorre V, Frances-Gomez C, Ferrer J, Forque L, Costa R, de la Asuncion C, Huntley D, Gozalbo-Rovira R, Buesa J, Gimenez E, Rodriguez-Diaz J, Geller R, Navarro D. Journal of Medical Virology. 2021 Apr;93(4):2301-2306. doi: 10.1002/jmv.26697. PMID: 33236799

The role of host glycobiology and gut microbiota in rotavirus and norovirus infection, an update. Peña-Gil N, Santiso-Bellón C, Gozalbo-Rovira R, Buesa J, Monedero V, Rodríguez-Díaz J. International Journal of Molecular Sciences. 2021 Dec 15;22(24):13473. doi: 10.3390/ijms222413473. PMID: 34948268

The Rotavirus Vaccine Landscape, an Update. Carcamo-Calvo R, Munoz C, Buesa J, Rodriguez-Diaz J, Gozalbo-Rovira R. Pathogens. 2021 Apr 26;10(5):520. doi: 10.3390/pathogens10050520. PMID: 33925924

Upper respiratory tract SARS-CoV-2 RNA loads in symptomatic and asymptomatic children and adults. Costa R, Bueno F, Albert E, Torres I, Carbonell-Sahuquillo S, Barres-Fernandez A, Sanchez D, Padron C, Colomina J, Lazaro Carreno M, Breton-Martinez J, Martinez-Costa C, Navarro D. Clinical Microbiology and Infection. 2021 Dec;27(12):1858.e1-1858.e7. doi: 10.1016/j.cmi.2021.08.001. PMID: 34384874

Usefulness of complementary test in the study of patients with chronic abdominal pain. Jimenez Candel MI, Salvador Pinto T, Garcia Peris M, Crehua Gaudiza E, Jovani Casano C, Moreno Ruiz MA, Hernandez Berto T, Largo Blanco E, Martinez Costa C. Anales de Pediatria. 2021 Jul;95(1):26-32. doi: 10.1016/j.anpede.2020.04.021. PMID: 34092539

Vitamin D status in pediatric and young adult cystic fibrosis patients. are the new recommendations effective?. Mangas-Sanchez C, Garriga-Garcia M, Serrano-Nieto MJ, Garcia-Romero R, Alvarez-Beltran M, Crehua-Gaudiza E, Munoz-Codoceo R, Suarez-Cortina L, Vicente-Santamaria S, Martinez-Costa C, Diaz-Martin JJ, Bousono-Garcia C, Gonzalez-Jimenez D. Nutrients. 2021 Dec 9;13(12):4413. doi: 10.3390/nu13124413. PMID: 34959965

Projects
Reference: AP-2021-004
Title: NEODIAG-VR: Realidad virtual para la formación multidisciplinar en neonatología
Funding body: Universidad de Valencia – INCLIVA
Principal Investigator: Jesús Gimeno Sancho, Javier Estañ Capell
Duration: 2021 – 2022
Total budget: 4.655 €
Reference: PI19/00354
Title: Efectividad de la vacunación antigripal y antineumocócica para prevenir la hospitalización en personas menores de 65 años que presentan condiciones de riesgo
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Ángela Domínguez García
Duration: 2020 – 2022
Total budget: 220.220 €
Reference: PI17/00565
Title: Evaluación de una intervención basada en la evidencia para reducir la bacteriemia asociada a catéter vascular central  en recién nacidos de muy bajo peso (RNMBP)
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Jose Ignacio Pijaón Zubizarreta
Duration: 2018 – 2020
Total budget: 146.108 €
Reference: PCIN-2017-117
Title: Obesidad materna y disfunción cognitiva en la descendencia: papel causa-efecto de la microbiota intestinal y prevención dietética temprana
Funding body: Ministerio de Economía y Competitividad
Principal Investigator: Consuelo Borrás Blasco
Duration: 2017 – 2022
Total budget: 143.000 €
Reference: INTIMIC-085
Title: GUTMOM: Maternal obesity and cognitive dysfunction in the offspring: cause-effect role of the GUT MicrobiOMe and early dietary prevention
Funding body: European Commission. JPI HDHL
Principal Investigator: Patricia Lozzo
Duration: 2017 – 2020
Total budget: 778.240 €
Reference: PI16/01471
Title: Diversidad genética y antigénica de norovirus humanos: estudio de anticuerpos séricos protectores y de la inmunidad celular en ratones y en pacientes infectados
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Buesa Gómez
Duration: 2017 – 2019
Total budget: 68.365 €
Reference: MAMI
Title: MAMI – The Power of Maternal Microbes on Infant Health
Funding body: European Commission
Principal Investigator: María Carmen Collado
Duration: 2015 – 2020
Total budget: 1.499.978 €
+ Info
Title: Adaptación transcultural y validación de tres scores para la detección de riesgo de desnutrición pediátrica durante la hospitalización (PNRS, STAMP y STRONGkids). Estimación de la incidencia de desnutrición en nuestro medio
Doctoral candidate: Balaguer López, Evelin
Director(s): Martínez Costa, Cecilia; Núñez Gómez, Francisco
Date of the defense: 24/02/2023
University: Universitat de València

Title: Estudio del desarrollo y la función renal, y de aspectos implicados en el síndrome metabólico del adulto, en gemelos con peso dispar al nacimiento. Valoración durante la edad pediátrica
Doctoral candidate: Marín Serra, Juan
Director(s): Hernández Marco, Roberto; Núñez Gómez, Francisco; Fons Moreno, Jaime
Date of the defense: 24/10/2022
University: Universitat de València

Title: Anomalías craneofaciales y dentales en una población de escolares nacidos pretérmino
Doctoral candidate: Peiró Guijarro, María Aurora
Director(s): Martínez Costa, Cecilia; Catalá Picarro, Montserrat; Martínez Rodríguez, Laura
Date of the defense: 25/03/2022
University: Universitat de València

Title: Efecto de la intervención nutricional en escolares y adolescentes con obesidad con y sin resistencia a la insulina
Doctoral candidate: Grattarola, Ana Paula
Director(s): Núñez Gómez, Francisco; Martínez Costa, Cecilia
Date of the defense: 11/01/2021
University: Universitat de València

Title: Aproximaciones moleculares al estudio de las interacciones de rotavirus y norovirus con el huésped
Doctoral candidate: Vila Vicent, Susana
Director(s): Rodríguez Díaz, Jesús; Buesa Gómez, Francisco Javier
Date of the defense: 05/11/2020
University: Universitat de València

Title: Aplicación de la termografía infrarroja en pediatría: análisis de las alteraciones de la microcirculación cutánea
Doctoral candidate: Benavent Casanova, Olga
Director(s): Núñez Gómez, Francisco; Cibrián Ortíz De Anda, Rosa; Salvador Palmer, María Rosario
Date of the defense: 23/07/2020
University: Universitat de València

Title: Antígenos histo-sanguíneos e infección por rotavirus
Doctoral candidate: Pérez Ortín, Raúl
Director(s): Buesa Gómez, Francisco Javier
Date of the defense: 15/01/2020
University: Universitat de València