Dr. José Carlos Monteagudo Castro

Principal Investigator
Research Group on Skin Cancer

Presentation

Principal
Investigator
Dr. José Carlos Monteagudo Castro

carlos.monteagudo@uv.es; cmonteag@uv.es

Publications
CD34-negative, STAT6-negative, low-grade, low-risk solitary fibrous tumor. Monteagudo C, Perez-Deben S, Perez-Roda I, Giner F, Machado I. American Journal of Surgical Pathology. 2024 Feb 1;48(2):247-249. doi: 10.1097/PAS.0000000000002087. PMID: 37345671

A spitzoid tumor dataset with clinical metadata and whole slide images for deep learning models. Mosquera-Zamudio A, Launet L, Del Amor R, Moscardo A, Colomer A, Naranjo V, Monteagudo C. Scientific Data. 2023 Oct 16;10(1):704. doi: 10.1038/s41597-023-02585-2. PMID: 37845235

Acquired aggressive multisystemic disseminated lobular capillary haemangioma: a life threatening disorder. Monteagudo C, Porcar-Saura S, Navarro S, Burgues O, Gonzalez J, Ferrandez A, Forner M. Pathology. 2023 Aug;55(5):729-732. doi: 10.1016/j.pathol.2022.11.014. PMID: 36894353

Diagnostic algorithm to subclassify atypical spitzoid tumors in low and high risk according to their methylation status. González-Muñoz J, Sánchez-Sendra B, Monteagudo C. International Journal of Molecular Sciences. 2023 Dec 25;25(1):318. doi: 10.3390/ijms25010318. PMID: 38203489

Eczematous dermatitis presenting as a clear cell acanthoma-like lesion on the nipple and areola. Ballesteros Redondo M, Fernandez Domper L, Monteagudo Castro C. Actas Dermo-Sifiliograficas. 2023 Mar 23:S0001-7310(23)00220-X. doi: 10.1016/j.ad.2022.06.028. PMID: 36965773

Lymphovascular invasion and high mitotic count are associated with increased risk of recurrence in pleomorphic dermal sarcoma. Pons Benavent M, Rios-Vinuela E, Nagore E, Monteagudo C, Aguerralde M, Mata Cano D, Llombart B, Serra-Guillen C, Pinazo Canales I, Requena C, Sanmartin O. Actas Dermo-Sifiliograficas. 2023 Jul-Aug;114(7):572-579. doi: 10.1016/j.ad.2023.04.018. PMID: 37088288

Lymphovascular invasion and high mitotic count are associated with increased risk of recurrence in pleomorphic dermal sarcoma. Pons Benavent M, Rios-Vinuela E, Nagore E, Monteagudo C, Aguerralde M, Mata Cano D, Llombart B, Serra-Guillen C, Pinazo Canales I, Requena C, Sanmartin O. Actas Dermo-Sifiliograficas. 2023 Jul-Aug;114(7):T572-T579. doi: 10.1016/j.ad.2023.06.010. PMID: 37302481

Perieccrine coil elastosis: an unusual and previously unrecognized aging-related phenomenon. Monteagudo C, Alvarez E. American Journal of Dermatopathology. 2023 Jan 1;45(1):58-61. doi: 10.1097/DAD.0000000000002300. PMID: 36484609

Atypical fibroxanthoma and pleomorphic dermal sarcoma: a two-center retrospective study of 74 cases. Rios-Vinuela E, Pons Benavent M, Monteagudo C, Nagore E, Sanmartin O. Actas Dermo-Sifiliograficas. 2022 Jun;113(6):654-656. doi: 10.1016/j.ad.2021.09.008. PMID: 35431058

Benign cephalic histiocytosis mimicking mastocytosis. Diaz E, Fernandez B, Castro C, Hernandez J. Actas Dermo-Sifiliograficas. 2022 Feb;113(2):195-198. doi: 10.1016/j.ad.2020.05.014. PMID: 35249694

Benign cephalic histiocytosis mimicking mastocytosis. Silva Diaz E, Vazquez Fernandez B, Monteagudo Castro C, Martin Hernandez J. Actas Dermo-Sifiliograficas. 2022 Feb;113(2):T195-T198. doi: 10.1016/j.ad.2022.02.001. PMID: 35244585

Clinical and pathological features of Merkel cell carcinoma: A 4-year follow-up observational retrospective study in Spain. Rios-Martin J, Rodriguez-Salas N, Vazquez-Doval F, Llombart B, Rojas-Ferrer N, Gonzalez-Vela M, Zulueta T, Monteagudo C, Aneiros-Fernandez J, Beato M, Carrillo R, Silva-Carmona M, Ayala M, Gallego E, Rodriguez-Peralto J, Fraga-Fernandez J, Fernandez-Figueras M, Barranco C, Cordoba A, Sanz-Zorrilla A, Ferrer B, Funez R, Santonja C, Saus C, Idoate M, Santos-Briz A, Onrubia J, Pinedo F, de Las Penas R. Cancer Epidemiology. 2022 Feb;76:102081. doi: 10.1016/j.canep.2021.102081. PMID: 34922051

Deep learning for skin melanocytic tumors in whole-slide images: a systematic review. Mosquera-Zamudio A, Launet L, Tabatabaei Z, Parra-Medina R, Colomer A, Moll J, Monteagudo C, Janssen E, Naranjo V. Cancers. 2022 Dec 21;15(1):42. doi: 10.3390/cancers15010042. PMID: 36612037

Fluorescent in situ hybridization (FISH): a useful diagnostic tool for childhood conjunctival melanoma. Moral R, Monteagudo C, Muriel J, Moreno L, Peiro A. European Journal of Ophthalmology. 2022 Nov;32(6):NP13-NP19. doi: 10.1177/11206721211030775. PMID: 34240653

Prognostic value of IGF2 mRNA-Binding Protein 3 (IGF2BP3) intratumoral expression in melanoma patients at the time of diagnosis: comparative analysis of rt-qpcr versus immunohistochemistry. Sanchez-Sendra B, Perez-Deben S, Gonzalez-Munoz JF, Murgui A, Monteagudo C. Cancers. 2022 May 7;14(9):2319. doi: 10.3390/cancers14092319. PMID: 35565448

The prognostic value of miR-125b, miR-200c and miR-205 in primary cutaneous malignant melanoma is independent of BRAF mutational status. Sanchez-Sendra B, Gonzalez-Munoz J, Perez-Deben S, Monteagudo C. Cancers. 2022 Mar 16;14(6):1532. doi: 10.3390/cancers14061532. PMID: 35326682

A heterozygous mutation in the RAG2 gene with cutaneous and systemic manifestations partially resembling Omenn syndrome. Estebanez A, Verdu-Amoros J, Silva E, Velasco R, Cuesta A, Monteagudo C, Martin J. Journal der Deutschen Dermatologischen Gesellschaft. 2021 Jun;19(6):906-908. doi: 10.1111/ddg.14383. PMID: 34096685

An attention-based weakly supervised framework for spitzoid melanocytic lesion diagnosis in whole slide images. Del Amor R, Launet L, Colomer A, Moscardo A, Mosquera-Zamudio A, Monteagudo C, Naranjo V. Artificial Intelligence in Medicine. 2021 Nov;121:102197. doi: 10.1016/j.artmed.2021.102197. PMID: 34763799

CCL27 Signaling in the Tumor Microenvironment. Martinez-Rodriguez M, Monteagudo C. Advances in Experimental Medicine and Biology. 2021;1302:113-132. doi: 10.1007/978-3-030-62658-7_9. PMID: 34286445

Cutaneous lymphadenoma is a distinct trichoblastoma-like lymphoepithelial tumor with diffuse androgen receptor immunoreactivity, notch1 ligand in reed-sternberg-like cells, and common EGFR somatic mutations. Monteagudo C, Funez R, Sanchez-Sendra B, Gonzalez-Munoz JF, Nieto G, Alfaro-Cervello C, Murgui A, Barr R. The American Journal of Surgical Pathology. 2021 Oct 1;45(10):1382-1390. doi: 10.1097/PAS.0000000000001727. PMID: 34232601

Folliculotropic mycosis fungoides with flexural eruptive cysts and comedones in a 14-year-old boy. Roca-Gines J, Alfaro-Cervello C, Sanchez-Arraez J, Torres-Navarro I, Navarro-Mira MA, Monteagudo C, Botella-Estrada R. American Journal of Dermatopathology. 2021 Sep 1;43(9):656-658. doi: 10.1097/DAD.0000000000001958. PMID: 33989213

Kutane und systemische veränderungen mit ähnlichkeiten zum omenn-syndrom bei heterozygoter mutation im RAG2-Gen. Estébanez A, Verdú-Amorós J, Silva E, Velasco R, Cuesta A, Monteagudo C, Martín JM. Journal der Deutschen Dermatologischen Gesellschaft. 2021 Jun;19(6):906-908. doi: 10.1111/ddg.14383_g. PMID: 34139086

Melanocytic Hyperactivation Simulating an Acral Lentiginous Melanoma in a Patient With Parkinson Disease Treated by Levodopa. Porcar Saura S, Guillen Climent S, Pinazo Canales M, Monteagudo C. American Journal of dermatopathology. 2021 Mar 1;43(3):238-241. doi: 10.1097/DAD.0000000000001807. PMID: 33595233

Painful cutaneous lesions on the hand palm after Takotsubo cardiomyopathy and coronary angiography. Guillen-Climent S, Garcia-Vazquez A, Benavent M, Saura S, Canales I, Monteagudo C. Clinical and Experimental Dermatology. 2021 Mar;46(2):387-390. doi: 10.1111/ced.14475. PMID: 33091167

Pseudoxanthoma elasticum-like syndrome with coagulation deficiency associated with carotid artery hypoplasia and a novel gamma-glutamyl carboxylase gene mutation. Guillen-Climent S, Garcia-Vazquez A, Silva E, Estebanez A, Peredo A, Ruiz M, Monteagudo C, Quiles M. International Journal of Dermatology. 2021 Jan;60(1):e13-e15. doi: 10.1111/ijd.15147. PMID: 32808310

Soft nodule on the heel in an elderly male patient: answer. Benavent M, Guillen-Climent S, Martinez-Casimiro L, Fabra M, Castro C. American Journal of Dermatopathology. 2021 Sep 1;43(9):674-675. doi: 10.1097/DAD.0000000000001882. PMID: 34411022

Soft nodule on the heel in an elderly male patient: challenge. Benavent M, Guillen-Climent S, Martinez-Casimiro L, Fabra M, Castro C. American Journal of Dermatopathology. 2021 Sep 1;43(9):e102-e103. doi: 10.1097/DAD.0000000000001883. PMID: 34411026

Projects
Reference: PI20/00094
Title: Análisis combinado por Inteligencia Artificial de marcadores epigenéticos e imágenes microscópicas digitalizadas de tumores melanocíticos ambiguos para optimizar su clasificación diagnóstica y pronóstica
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Carlos Monteagudo Castro
Duration: 2021 – 2023
Total budget: 220.220 €
Reference: INNEST/2021/302/58
Title: Sistema de visión artificial aumentada para la caracterización molecular y morfológica del cáncer de piel
Funding body: Agencia Valenciana de la Innovación-AVI Generalitat Valenciana
Principal Investigator: Carlos Monteagudo Castro
Duration: 2021 – 2023
Total budget: 192.869 €
Reference: 860627- CLARIFY
Title: Cloud Artificial Intelligence for pathology-CLARIFY
Funding body: European Commission
Principal Investigator: Carlos Monteagudo Castro
Duration: 2019 – 2023
Total budget: 252000
Reference: PI17/02019
Title: electrónicos hasta los datos MULTI-ómic
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Carlos Monteagudo Castro
Duration: 2018 – 2021
Total budget: 99.220 €
+ Info
Title: Análisis comparativo de perfiles proteómicos endometriales y estudio del efecto disruptor del cobre y plomo sobre la receptividad endometrial
Doctoral candidate: Pérez Debén, Silvia
Director(s): Domínguez Hernández, Francisco; Remohí Giménez, José
Date of the defense: 02/06/2022
University: Universitat de València