Research Group on Cardiac Experimental Electrophysiology

Cardiovascular Area

Publication of the results obtained on using the 1,4-benzothiazepine derivative JTV-519 to modify the proarrhythmogenic manifestations of mechanoelectric feedback and continuation of the programmed experimental series to analiyze the effects of KN-93, carvedilol and analogues, late Na+ current inhibitors and the Nitric Oxide carrier S-nitrosoglutathione

– Continuation of the analysis of the effects of modifications of the basic electrophysiological properties on the processes involved in the induction and maintenance of ventricular fibrillation

– Analysis of the electrophysiological effects of chronic physical exercise and its protective effect against arrhythmias, the influence of the cardiac nervous system and mitochondrial oxidative stress and the involvement of the IKATP current

– Development of instruments for recording, processing and analysing cardiac electrophysiological signals obtained with mapping systems

– Progressive development of the experimental series aimed to study the mechanisms involved in the deterioration of the systolic function, fibrosis and the inducibility of arrhythmias in a chronic model of infarction

– Progressive development of an experimental model of metabolic syndrome to analyze the electrophysiological modifications and the inducibility of cardiac arrhythmias

Coordinator
Dr. Francisco Javier Chorro Gascó
francisco.j.chorro@uv.es; fchorro@uv.es

RESEARCHERS
Leading, R4

Francisco Javier Chorro Gascó    
Antonio M. Alberola Aguilar
Luis Such Belenguer

Established, R3
Recognised/Emerging, R2

Manuel Zarzoso Muñoz
Irene del Canto Serrano
Isabel Trapero Gimeno
Luis Such Miquel
Óscar Julián Arias Mutis
Patricia Genovés Martínez

First Stage, R1

Johan E. Ortiz Guzmán

STAFF
Collaborating Researchers
Nurse
Technicians
Administrative assistant
Publications
Analysis and prevention of falls among community-dwelling older adults in southern Thailand. Pantong U, Trapero I, Jareaprapal U. Journal of Advanced Nursing. 2023 Nov 10. doi: 10.1111/jan.15945. PMID: 37950381

Association between COL5a1, COL11a1, and COL11a2 gene variations and rotator cuff tendinopathy in young athletes. Alakhdar Y, Cook J, Gallego D, Querol F, Chulvi-Medrano I, Alberola A, Hernández-Sánchez S. Clinical Journal of Sport Medicine. 2023 Sep 1;33(5):e152-e156. doi: 10.1097/JSM.0000000000000937. PMID: 34009784

Cardiac magnetic resonance outperforms echocardiography to predict subsequent implantable cardioverter defibrillator therapies in ST-segment elevation myocardial infarction patients. Marcos-Garces V, Perez N, Gavara J, Lopez-Lereu M, Monmeneu J, Rios-Navarro C, de Dios E, Merenciano-Gonzalez H, Gabaldon-Perez A, Ferrero-de-Loma-Osorio A, Martinez-Brotons A, Bondanza L, Sanchez-Gomez J, Albiach C, Nunez J, Bayes-Genis A, Chorro F, Ruiz-Granell R, Bodi V. Frontiers in Cardiovascular Medicine. 2023 Feb 3;10:991307. doi: 10.3389/fcvm.2023.991307. PMID: 36818338

Changes in the extracellular matrix at microvascular obstruction area after reperfused myocardial infarction: A morphometric study. Blazquez-Bujeda A, Ortega M, de Dios E, Gavara J, Perez-Sole N, Molina-Garcia T, Marcos-Garces V, Diaz A, Chorro F, Rios-Navarro C, Bodi V, Ruiz-Sauri A. Annals of Anatomy-Anatomischer Anzeiger. 2023 Jul 26;250:152138. doi: 10.1016/j.aanat.2023.152138. PMID: 37506775

Differences in long-term heart rate variability between subjects with and without metabolic syndrome: a systematic review and meta-analysis. Ortiz-Guzman J, Molla-Casanova S, Arias-Mutis O, Bizy A, Calvo C, Alberola A, Chorro F, Zarzoso M. Journal of Cardiovascular Development And Disease. 2023 May 9;10(5):203. doi: 10.3390/jcdd10050203. PMID: 37233170

Effect of serum from patients with ST-segment elevation myocardial infarction on endothelial cells. Rios-Navarro C, Gavara J, Dios E, Perez-Sole N, Molina-Garcia T, Marcos-Garces V, Ruiz-Sauri A, Bayes-Genis A, Carrion-Valero F, Chorro F, Bodi V. Revista Espanola de Cardiologia (English ed.). 2023 Sep 9;S1885-5857(23)00238-4. doi: 10.1016/j.rec.2023.08.004. PMID: 37696331

Evaluating video virtual reality teaching for nursing students. Trapero I, Sánchez-Martínez V, Cauli O, Buigues C. Medical Education. 2023 Nov;57(11):1157-1158. doi: 10.1111/medu.15234. PMID: 37718266

Evaluation and assessment of clique arrangements for the estimation of omnipolar electrograms in high density electrode arrays: an experimental animal model study. Ruiperez-Campillo S, Crespo M, Tormos A, Guill A, Cebrian A, Alberola A, Heimer J, Chorro F, Millet J, Castells F. Physical and Engineering Sciences in Medicine. 2023 Sep;46(3):1193-1204. doi: 10.1007/s13246-023-01287-8. PMID: 37358782

Impact of persistent microvascular obstruction late after STEMI on AdverseLV remodeling: a CMR Study. Bodi V, Gavara J, Lopez-Lereu M, Monmeneu J, de Dios E, Perez-Sole N, Bonanad C, Marcos-Garces V, Canoves J, Minana G, Nunez J, Moratal D, Chorro F, Rodriguez-Palomares J, Freixa A, Borras R, Ortiz-Perez J, Rios-Navarro C. JACC. Cardiovascular Imaging. 2023 Jul;16(7):919-930. doi: 10.1016/j.jcmg.2023.01.021. PMID: 37052556

Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial-IRON trial. Santas E, Del Canto I, Cardells I, Miñana G, Llácer P, Almenar L, Fácila L, Maceira A, Sanchis J, Núñez J. ESC Heart Failure. 2023 Dec 20. doi: 10.1002/ehf2.14630. PMID: 38115745

Improvement of vascular insulin sensitivity by ranolazine. Guerra-Ojeda S, Jorda A, Aldasoro C, Vila J, Valles S, Arias-Mutis O, Aldasoro M. International Journal of Molecular Sciences. 2023 Aug 31;24(17):13532. doi: 10.3390/ijms241713532. PMID: 37686345

Modifications of long-term heart rate variability produced in an experimental model of diet-induced metabolic syndrome. Lozano W, Ortiz-Guzman J, Arias-Mutis O, Bizy A, Genovés P, Such-Miquel L, Alberola A, Chorro F, Zarzoso M, Calvo C. Interface Focus. 2023 Dec 15;13(6):20230030. doi: 10.1098/rsfs.2023.0030. PMID: 38106920

MRI investigation of the differential impact of left ventricular ejection fraction after myocardial infarction in elderly vs. nonelderly patients to predict readmission for heart failure. Marcos Garces V, Merenciano Gonzalez H, Gavara J, Gabaldon Perez A, Lopez Lereu MP, Monmeneu JV, Nunez J, Perez N, Rios Navarro C, de Dios E, Chorro FJ, Valente F, Lorenzatti D, Domenech Ximenos B, Alonso Tello A, Maymi Ballesteros M, Rello Sabate P, Morr CI, Ortiz Perez JT, Rodriguez Palomares JF, Bodi V. Journal of Magnetic Resonance Imaging. 2023 Nov;58(5):1507-1518. doi: 10.1002/jmri.28632. PMID: 36748793

Noncardiovascular morbidity and mortality across left ventricular ejection fraction catefories following hospitalization for heart failure. Santas E, Llacer P, Palau P, de la Espriella R, Minana G, Lorenzo M, Marin G, Miro O, Chorro F, Genis A, Sanchis J, Nunez J. Revista Espanola de Cardiologia (English ed.). 2023 Jun 12;S1885-5857(23)00158-5. doi: 10.1016/j.rec.2023.05.005. PMID: 37315921

Novel targets regulating the role of endothelial cells and angiogenesis after infarction: a rna sequencing analysis. Ortega M, Molina-Garcia T, Gavara J, de Dios E, Perez-Sole N, Marcos-Garces V, Chorro F, Rios-Navarro C, Ruiz-Sauri A, Bodi V. International Journal of Molecular Sciences. 2023 Oct 28;24(21):15698. doi: 10.3390/ijms242115698. PMID: 37958681

Risk of death associated with incident heart failure in patients with known or suspected chronic coronary síndrome. Nunez J, Lorenzo M, Minana G, Palau P, Monmeneu JV, Lopez-Lereu MP, Gavara J, Marcos-Garces V, Rios-Navarro C, Perez N, de Dios E, Nunez E, Sanchis J, Chorro FJ, Bayes-Genis A, Bodi V. ESC Heart Failure. 2023 Feb;10(1):264-273. doi: 10.1002/ehf2.14179. PMID: 36196583

Short-course high-intensity statin treatment during admission for myocardial infarction and LDL-cholesterol reduction-impact on tailored lipid-lowering therapy at discharge. Marcos-Garces V, Merenciano-Gonzalez H, Martinez Mas M, Palau P, Climent Alberola J, Perez N, Lopez-Bueno L, Esteban Argente M, Valls Reig M, Munoz Alcover R, Pradillas Contreras I, Arizon Benito A, Paya Rubio A, Rios-Navarro C, de Dios E, Gavara J, Chorro F, Sanchis J, Bodi V. Journal of Clinical Medicine. 2023 Dec 25;13(1):127. doi: 10.3390/jcm13010127. PMID: 38202134

Short-term heart rate variability in metabolic syndrome: a systematic review and meta-analysis. Ortiz-Guzman J, Molla-Casanova S, Serra-Ano P, Arias-Mutis O, Calvo C, Bizy A, Alberola A, Chorro F, Zarzoso M. Journal of Clinical Medicine. 2023 Sep 19;12(18):6051. doi: 10.3390/jcm12186051. PMID: 37762990

Antithrombotic therapy in elderly patients with acute coronary síndromes. Bonanad C, Esteve-Claramunt F, Garcia-Blas S, Ayesta A, Diez-Villanueva P, Perez-Rivera J, Ferreiro J, Canoves J, Lopez-Fornas F, Sole A, Raposerias S, Vivas D, Blanco R, Berroteran D, Cordero A, Nunez J, Facila L, Nunez-Gil I, Gorriz J, Bodi V, Martinez-Selles M, Nodar J, Chorro F. Journal of Clinical Medicine. 2022 May 26;11(11):3008. doi: 10.3390/jcm11113008. PMID: 35683397

Applicability of echocardiographic strict negative criteria for suspected infective endocarditis. Marcos-Garces V, Gabaldon-Perez A, Merenciano-Gonzalez H, Soler M, Lorenzo-Hernandez M, Nunez-Marin G, de la Espriella R, Bonanad C, Nunez J, Chorro FJ, Bodi V, Santas E. American Journal of Cardiology. 2022 Jan 1;162:156-162. doi: 10.1016/j.amjcard.2021.09.012. PMID: 34728063

Carbohydrate antigen 125 and risk of heart failure readmissions in patients with heart failure and preserved ejection fraction. Minana G, de la Espriella R, Palau P, Llacer P, Nunez E, Santas E, Valero E, Lorenzo M, Nunez G, Bodi V, Heredia R, Sanchis J, Bayes-Genis A, Chorro F, Nunez J. Scientific Reports. 2022 Jan 25;12(1):1344. doi: 10.1038/s41598-022-05328-2. PMID: 35079082

Combined assessment of stress cardiovascular magnetic resonance and angiography to predict the effect of revascularization in chronic coronary syndrome patients. Gavara J, Perez N, Marcos-Garces V, Monmeneu J, Lopez-Lereu M, Rios-Navarro C, de Dios E, Bonanad C, Canoves J, Moratal D, Palau P, Minana G, Nunez J, Chorro F, Bodi V. European Journal of Preventive Cardiology. 2022 Mar 11;29(2):407-416. doi: 10.1093/eurjpc/zwab170. PMID: 34686874

EpCAM and microvascular obstruction in patients with STEMI: a cardiac magnetic resonance study. Rios-Navarro C, Gavara J, Nunez J, Revuelta-Lopez E, Monmeneu JV, Lopez-Lereu MP, de Dios E, Perez-Sole N, Vila JM, Oltra R, Chorro FJ, Bayes-Genis A, Bodi V. Revista Espanola de Cardiologia (English ed.). 2022 May;75(5):384-391. doi: 10.1016/j.rec.2021.04.006. PMID: 34045168

Evaluation of the effectiveness of breastfeeding as a factor in the prevention of breast cancer. Cabrera L, Trapero I. Endocrine, Metabolic & Immune Disorders Drug Targets. 2022;22(1):15-25. doi: 10.2174/1871530321666210427083707. PMID: 33906596

Evaluation of the use of dual antiplatelet therapy beyond the first year after acute coronary syndrome. Bonanad C, Raposeiras-Roubin S, Garcia-Blas S, Nunez-Gil I, Vergara-Uzcategui C, Diez-Villanueva P, Baneras J, Molins C, Aboal J, Carreras J, Bodi V, Gabaldon-Perez A, Mateus-Porta G, Barcia J, Martinez-Selles M, Chorro F, Ariza-Sole A. Journal of Clinical Medicine. 2022 Mar 17;11(6):1680. doi: 10.3390/jcm11061680. PMID: 35330004

Exercise ECG Testing and stress cardiac magnetic resonance for risk prediction in patients with chronic coronary syndrome. Marcos-Garces V, Merenciano-Gonzalez H, Gabaldon-Perez A, Nunez-Marin G, Lorenzo-Hernandez M, Gavara J, Perez N, Rios-Navarro C, De Dios E, Bonanad C, Racugno P, Lopez-Lereu MP, Monmeneu JV, Chorro FJ, Bodi V. Journal of Cardiopulmonary Rehabilitation and Prevention. 2022 Jan 1;42(1):E7-E12. doi: 10.1097/HCR.0000000000000621. PMID: 34561369

Fourier analysis of collagen bundle orientation in myocardial infarction scars. Marcos-Garces V, Rios-Navarro C, Gomez-Torres F, Gavara J, de Dios E, Diaz A, Minana G, Chorro F, Bodi V, Ruiz-Sauri A. Histochemistry and Cell Biology. 2022 Nov;158(5):471-483. doi: 10.1007/s00418-022-02132-x. PMID: 35948735

Magnetic resonance assessment of left ventricular ejection fraction at any time post-infarction for prediction of subsequent events in a large multicenter STEMI Registry. Gavara J, Marcos-Garces V, Lopez-Lereu, MP, Monmeneu JV, Rios-Navarro C, de Dios E, Perez N, Merenciano H, Gabaldon A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Nunez E, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Rodriguez-Palomares JF, Ortiz-Perez JT, Bodi V. Journal of Magnetic Resonance Imaging. 2022 Aug;56(2):476-487. doi: 10.1002/jmri.27789. PMID: 34137478

Nurse-led and interdisciplinary secondary cardiovascular prevention programmes: Spanish cohort of the EUROACTION Project. Cristina B, Isabel T, Antonio D, Antonio S, Catriona J, David W, Ana Q. Endocrine, Metabolic & Immune Disorders Drug Targets. 2022;22(13):1319-1329. doi: 10.2174/1871530322666220331154354. PMID: 35362378

Prognostic value of cardiac magnetic resonance early after ST-segment elevation myocardial infarction in older patients. Gabaldón-Pérez A, Marcos-Garcés V, Gavara J, López-Lereu MP, Monmeneu JV, Pérez N, Ríos-Navarro C, De Dios E, Merenciano-González H, Cànoves J, Racugno P, Bonanad C, Minana G, Núnez J, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Ortiz-Pérez JT, Rodríguez-Palomares JF, Bodí V. Age and Ageing. 2022 Nov 2;51(11):afac248. doi: 10.1093/ageing/afac248. PMID: 36436010

Residual ST-segment elevation to predict long-term clinical and CMR-derived outcomes in STEMI. Merenciano-Gonzalez H, Marcos-Garces V, Gavara J, Pedro-Tudela A, Lopez-Lereu M, Monmeneu J, Perez N, Rios-Navarro C, de Dios E, Gabaldon-Perez A, Albiach C, Racugno P, Bonanad C, Canoves J, Chorro F, Bodi V. Scientific Reports. 2022 Dec 17;12(1):21813. doi: 10.1038/s41598-022-26082-5. PMID: 36528716

Risk score for early risk prediction by cardiac magnetic resonance after acute myocardial infarction. Marcos-Garces V, Perez N, Gavara J, Lopez-Lereu MP, Monmeneu JV, Rios-Navarro C, de Dios E, Merenciano-Gonzalez H, Gabaldon-Perez A, Canoves J, Racugno P, Bonanad C, Minana G, Nunez J, Moratal D, Chorro FJ, Valente F, Lorenzatti D, Ortiz-Perez JT, Rodriguez-Palomares JF, Bodi V. International Journal of Cardiology. 2022 Feb 15;349:150-154. doi: 10.1016/j.ijcard.2021.11.050. PMID: 34826497

Salivary IL-6 concentration is associated with frailty syndrome in older individuals. Gomez-Rubio P, Trapero I, Cauli O, Buigues C. Diagnostics. 2022 Jan 5;12(1):117. doi: 10.3390/diagnostics12010117. PMID: 35054284

Sex effect in the decision to perform invasive coronary angiography in patients with chronic coronary syndrome after undergoing vasodilator stress MRI. Palau P, Nunez J, Monmeneu J, Lopez-Lereu M, Gavara J, Rios-Navarro C, de Dios E, Perez-Sole N, Marcos-Garces V, Dominguez E, Moratal D, Canoves J, Minana G, Chorro F, Bodi V. Journal of Magnetic Resonance Imaging. 2022 Dec;56(6):1680-1690. doi: 10.1002/jmri.28163. PMID: 35344231

Sex-related differences in mortality following admission for acute heart failure across the left ventricular ejection fraction spectrum. Santas E, Palau P, Llacer P, de la Espriella R, Minana G, Nunez-Marin G, Lorenzo M, Heredia R, Sanchis J, Chorro FJ, Bayes-Genis A, Nunez J. Journal of the American Heart Association. 2022 Jan 4;11(1):e022404. doi: 10.1161/JAHA.121.022404. PMID: 34927464

Short-term changes in left and right ventricular cardiac magnetic resonance feature tracking strain following ferric carboxymaltose in patients with heart failure: a substudy of the Myocardial-IRON Trial. Del Canto I, Santas E, Cardells I, Minana G, Palau P, Llacer P, Facila L, Lopez-Vilella R, Almenar L, Bodi V, Lopez-Lereu M, Monmeneu J, Sanchis J, Moratal D, Maceira A, de la Espriella R, Chorro F, Bayes-Genis A, Nunez J. Journal of the American Heart Association. 2022 Apr 5;11(7):e022214. doi: 10.1161/JAHA.121.022214. PMID: 35301854

Smoking in hospitalized patients. A great opportunity. Carrion Valero F, Martinez Gonzalez D, Bobes-Bascaran M, Galan Gil G, Ortega Serrano J, Chorro Gasco F, Bobes J, Jimenez Ruiz C. Adicciones. 2022 Feb 16;34(1):13-22. doi: 10.20882/adicciones.1358. PMID: 32677696

Stress cardiac magnetic resonance for mortality prediction and decision-making: registry of 2496 elderly patients with chronic coronary syndrome. Gabaldon-Perez A, Bonanad C, Garcia-Blas S, Gavara J, Rios-Navarro C, Perez-Sole N, de Dios E, Marcos-Garces V, Merenciano-Gonzalez H, Monmeneu J, Lopez-Lereu M, Nunez J, Chorro F, Bodi V. Revista Espanola de Cardiologia (english Ed.). 2022 Mar;75(3):223-231. doi: 10.1016/j.rec.2021.08.004. PMID: 34548244

Antigen carbohydrate 125 as a biomarker in heart failure: a narrative review. Nunez J, de la Espriella R, Minana G, Santas E, Llacer P, Nunez E, Palau P, Bodi V, Chorro F, Sanchis J, Lupon J, Bayes-Genis A. European Journal of Heart Failure. 2021 Sep;23(9):1445-1457. doi: 10.1002/ejhf.2295. PMID: 34241936

Coronary Revascularization and Long-Term Survivorship in Chronic Coronary Syndrome. Gabaldon-Perez A, Marcos-Garces V, Gavara J, Rios-Navarro C, Minana G, Bayes-Genis A, Husser O, Sanchis J, Nunez J, Chorro F, Bodi V. Journal of Clinical Medicine. 2021 Feb 5;10(4):610. doi: 10.3390/jcm10040610. PMID: 33562869

Early urinary sodium trajectory and risk of adverse outcomes in acute heart failure and renal dysfunction. De La Espriella Juan R, Nuñez Benito E, Llàcer P, Garcia Blas S, Ventura Haro S, Núñez J, Sánchez R, Facila De La Esperanza R, Vaquer Santamaria J, Bodí Peris V, Santas Olmeda E, Miñana Escriva G, Mollar Fernandez A, Núñez Marín G, Chorro Gascó F, Górriz Teruel J, Sanchis Fores J, Bayés-Genis A, Nuñez Villota J. Revista Espanola de Cardiologia (English ed.). 2021 Jul;74(7):616-623. doi: 10.1016/j.rec.2020.06.004. PMID: 32624444

Effect of beta-blocker withdrawal on functional capacity in heart failure and preserved ejection fraction. Palau P, Seller J, Dominguez E, Sastre C, Ramon JM, Espriella R, Santas E, Minana G, Bodi V, Sanchis J, Valle A, Chorro FJ, Llacer P, Bayes-Genis A, Nunez J. Journal of the American College of Cardiology. 2021 Nov 23;78(21):2042-2056. doi: 10.1016/j.jacc.2021.08.073. PMID: 34794685

Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain. A randomized controlled trial. Espí López G, Aguilar Rodríguez M, Zarzoso Muñoz M, Serra Año M, Martinez De La Fuente J, Inglés De La Torre M, Marques-Sule E. European Journal of Physical and Rehabilitation Medicine. 2021 Jun;57(3):397-405. doi: 10.23736/S1973-9087.20.06302-9. PMID: 33047944

Homocysteine and long-term recurrent infarction following an acute coronary síndrome. Miñana Escriva G, Gil Cayuela C, Facila De La Esperanza R, Bodí Peris V, Valero Picher E, Mollar Fernandez A, Marco M, Garcia-Ballester T, Zorio B, Marti-Cervera J, Nuñez Benito E, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Cardiology Journal. 2021;28(4):598-606. doi: 10.5603/CJ.a2020.0170. PMID: 33346372

Hypoplasia of the posterior mitral valve leaflet: Don’t forget to look beyond the mitral valve. Gabaldón-Pérez A, Marcos-Garcés V, Muñoz Gil J, Chorro Gascó FJ, Santas E. Echocardiography. 2021 Jan;38(1):142-143. doi: 10.1111/echo.14910. PMID: 33107084

Immunoglobulin G4-related aortitis and severe aortic valve stenosis treated with transcatheter aortic valve replacement and immunosuppression. Viana D, Marcos-Garces V, Blas S, Fores J, Romano J, Baena J, Giner M, Suarez N, Chorro F, Fornas F. Canadian Journal of Cardiology. 2021 Nov;37(11):1873-1876. doi: 10.1016/j.cjca.2021.07.015. PMID: 34333027

Ischemia-reperfusion injury to coronary arteries: comprehensive microscopic study after reperfused myocardial infarction. Rios-Navarro C, Daugbouche-Rubio N, Gavara J, de Dios E, Perez N, Vila JM, Chorro FJ, Ruiz-Sauri A, Bodi V. Annals of Anatomy. 2021 Nov;238:151785. doi: 10.1016/j.aanat.2021.151785. PMID: 34144157

Longitudinal strain in remote non-infarcted myocardium by tissue tracking CMR: characterization, dynamics, structural and prognostic implications. GAVARA DOÑATE J, Rodriguez-Palomares J, Rios Navarro C, Valente F, Monmeneu J, Lopez-Lereu M, Ferreira-Gonzalez I, Garcia Del Blanco B, Otaegui I, Canoves Femenia J, De Dios Lluch E, Pérez Solé N, Racugno P, Bonanad Lozano C, Miñana Escriva G, Marcos Garcés V, Barrabes J, Evangelista A, Moratal D, Bayes-Genis A, Nuñez Villota J, Chorro Gascó F, Bodí Peris V. The International Journal Of Cardiovascular Imaging. 2021 Jan;37(1):241-253. doi: 10.1007/s10554-020-01890-w. PMID: 32488452

Matrix metalloproteinase-12 cleaved fragment of titin as a predictor of functional capacity in patients with heart failure and preserved ejection fraction. Palau Sampio P, Reese-Petersen A, Dominguez E, Ramón Ferrandis J, Lopez L, Mollar Fernandez A, Chorro Gascó F, Sanchis Fores J, Nuñez Villota J. Scandinavian Cardiovascular Journal. 2021 Feb;55(1):9-14. doi: 10.1080/14017431.2020.1831052. PMID: 33030056

Native mitral valve endocarditis complicated with abscess and fistulas: Diagnosis by three-dimensional transesophageal echocardiography. Gabaldon-Perez A, de la Espriella R, Merenciano-Gonzalez H, Santas E, Chorro F. Revista Portuguesa de Cardiologia. 2021 Aug 30:S0870-2551(21)00345-0. doi: 10.1016/j.repc.2020.06.023. PMID: 34474955

Overexpression of genes involved in lymphocyte activation and regulation are associated with reduced CRM-derived cardiac remodelling after STEMI. de Dios E, Rios-Navarro C, Perez-Sole N, Gavara J, Marcos-Garces V, Forteza M, Oltra R, Vila J, Chorro F, Bodi V. International Immunopharmacology. 2021 Mar 4;95:107490. doi: 10.1016/j.intimp.2021.107490. PMID: 33677257

PPARgamma as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits. Guerra-Ojeda S, Marchio P, Gimeno-Raga M, Arias-Mutis O, San-Miguel T, Valles S, Aldasoro M, Vila J, Zarzoso M, Mauricio M. Atherosclerosis. 2021 Aug 5;332:16-23. doi: 10.1016/j.atherosclerosis.2021.08.006. PMID: 34375909

Psycho-Social Factors in Patients with Cardiovascular Disease Attending a Family-Centred Prevention and Rehabilitation Programme: EUROACTION Model in Spain. Buigues C, Queralt A, De Velasco J, Salvador-Sanz A, Jennings C, Wood D, Trapero I. Life. 2021 Jan 26;11(2):89. doi: 10.3390/life11020089. PMID: 33530575

Right heart dysfunction and readmission risk across left ventricular ejection fraction status in patients with acute heart failure. Santas E, Minana G, Palau P, De La Espriella R, Lorenzo M, Nunez G, Sanchis J, Chorro FJ, Bayes-Genis A, Nunez J. Journal of Cardiac Failure. 2021 Oct;27(10):1090-1098. doi: 10.1016/j.cardfail.2021.06.020. PMID: 34273477

Right ventricular function and iron deficiency in acute heart failure. Miñana Escriva G, Santas Olmeda E, De La Espriella Juan R, Nunez E, Lorenzo Hernández M, Núñez Marín G, Valero Picher E, Bodí Peris V, Chorro Gascó F, Sanchis Fores J, Cohen-Solal A, Bayes-Genis A, Nuñez Villota J. European heart journal. Acute cardiovascular care. 2021 May 25;10(4):406-414. doi: 10.1093/ehjacc/zuaa028. PMID: 33620455

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

Sex differences on new-onset heart failure in patients with known or suspected coronary artery disease. Nunez J, Lorenzo M, Minana G, Palau P, Monmeneu JV, Lopez-Lereu MP, Gavara J, Marcos-Garces V, Rios-Navarro C, Perez N, de Dios E, Nunez E, Sanchis J, Chorro FJ, Bayes-Genis A, Bodi V. European Journal of Preventive Cardiology. 2021 Dec 29;28(15):1711-1719. doi: 10.1093/eurjpc/zwab078. PMID: 33970216

Suspected Kawasaki disease diagnosed in the adulthood. Severe sequelae in the coronary arteries. Lorenzo-Hernandez M, Marcos-Garces V, Lopez-Fornas F, Valero E, Bodi V, Chorro F. Coronary Artery Disease. 2021 Dec 1;32(8):741-743. doi: 10.1097/MCA.0000000000001029. PMID: 33587361

The beneficial effect of physical exercise on inflammatory makers in older individuals. Gomez-Rubio P, Trapero Gimeno I. Endocrine Metabolic & Immune Disorders-Drug Targets. 2021;21(6):1008-1016. doi: 10.2174/1871530320666200606225357. PMID: 32504508

Trend in Spanish cardiology research and global comparative analysis of major topics. Chorro, FJ, Alonso-Arroyo A, Aleixandre-Benavent R. Revista Espanola de Cardiologia. 2021 Nov;74(11):909-918. doi: 10.1016/j.rec.2020.12.001. PMID: 33390334

Projects
Reference: PI21/01984
Title: Efectos de la inhibición de SGLT2 sobre el remodelado auricular producido por el síndrome metabólico y su sustrato arritmogénico. Estudio experimental
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Chorro Gascó, Manuel Zarzoso Muñoz
Duration: 2022 – 2024
Total budget: 99.220 €
Reference: SEC/FEC-INV-CLI 21/024
Title: Resonancia magnética cardíaca de estrés con vasodilatadores para predecir la mortalidad a largo plazo en un amplio registro retrospectivo de pacientes con cardiopatía isquémica conocida o sospechada
Funding body: Sociedad Española de Cardiología
Principal Investigator: Vicent Bodí Peris
Duration: 2021 – 2022
Total budget: 15.000 €
Reference: PI18/01620
Title: Modificacion de los efectos pro-arritmicos inducidos por la sobrecarga mecanica o el remodelado ventricular
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Chorro Gascó
Duration: 2019 – 2021
Total budget: 129.470 €
Reference: PROMETEO/2018/078
Title: Mecanismos protectores frente ala muerte cardiaca súbita de causa arrítmica
Funding body: Conselleria de Educación, Cultura y Deporte
Principal Investigator: Francisco Javier Chorro Gascó
Duration: 2018 – 2021
Total budget: 275.859 €
Reference: CB16/11/00486
Title: CIBER Enfermedades Cardiovasculares (CIBERCV)
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Chorro Gascó
Duration: 2017 –
Total budget:
Reference: PIE15/00013
Title: A multidisciplinary Project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Vicente Bodí Peris
Duration: 2016 – 2019
Total budget: 589.050 €
Reference: PI15/01408
Title: Efectos de la inhibición de la desacetilación de las histonas en el remodelado post-infarto del sustrato arritmogénico
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Francisco Javier Chorro Gascó
Duration: 2016 – 2019
Total budget: 93.170 €
+ Info
Title: Estudio del remodelado eléctrico cardiaco producido en un modelo experimental de síndrome metabólico y su implicación en la génesis de arritmias
Doctoral candidate: Arias Mutis, Óscar Julián
Director(s): Zarzoso Muñoz, Manuel; Calvo Sáiz, Conrado Javier
Date of the defense: 12/06/2023
University: University de Valencia

Title: Valor pronóstico de los parámetros de deformación miocárdica en una cohorte de pacientes con insuficiencia cardíaca crónica estable
Doctoral candidate: González D’ Gregorio, Jessika
Director(s): Nuñez Villota, Julio; Chorro Gascó, Francisco Javier
Date of the defense: 08/05/2023
University: Universitat de València

Title: Optimización del diagnóstico de la endocarditis infecciosa en un hospital terciario
Doctoral candidate: Falomir Salcedo, Patricia
Director(s): Blanes Juliá, Francisco Marino; Gómez Ruíz, María Dolores; Chorro Gascó, Francisco Javier
Date of the defense: 08/03/2023
University: Universitat de València

Title: Efectos electrofisiológicos intrínsecos del ejercicio físico crónico sobre el miocardio ventricular normóxico y tras isquemia regional aguda: implicación del canal katp. estudio en corazón aislado de conejo
Doctoral candidate: Gallego Rojas, Nathalia
Director(s): Guerrero Martínez, Juan; Parra Giraldo, Germán; Such Belenguer, Luis
Date of the defense: 22/07/2021
University: Universitat de València

Title: Efectos de la inhibición de la desacetilación de las histonas en el remodelado post-infarto del sustrato arritmogénico
Doctoral candidate: Genovés Martínez, Patricia
Director(s): Chorro Gascó, Francisco Javier; Such Belenguer, Luis; Del Canto Serrano, Irene
Date of the defense: 27/04/2021
University: Universitat de València

Title: Cambios en la activación electromiográfica de la musculatura de codo en sujetos sanos comparada con la activación muscular en sujetos con tendinopatía y la influencia de la aplicación de punción seca en la misma
Doctoral candidate: Hanna, Fredy
Director(s): Alakhdar Mohmara, Yasser; Alberola Aguilar, Antonio
Date of the defense: 23/04/2021
University: Universitat de València

Title: Estudio de la función miocárdica en la enfermedad renal crónica avanzada y en la terapia de sustitución renal
Doctoral candidate: Melero Lloret, Joana
Director(s): Chorro Gascó, Francisco Javier; Soriano Navarro, Carlos Joaquín
Date of the defense: 26/03/2021
University: Universitat de València

Title: Inherited arrhythmogenic cardiac diseases and the KIR2.1-NAV1.5 channelosome
Doctoral candidate: Jalife Sacal, José
Director(s): Chorro Gascó, Francisco Javier; Such Belenguer, Luís
Date of the defense: 18/12/2020
University: Universitat de València

Title: Implicación del canal katp en las modificaciones que la realización de ejercicio físico crónico produce sobre algunas propiedades electrofisiológicas en el miocardio. Estudio en corazón aislado sometido a isquemia global aguda
Doctoral candidate: Soler López, Carlos
Director(s): Such Belenguer, Luis; Chorro Gascó, Francisco Javier; Iradi Casal, Antonio
Date of the defense: 17/04/2019
University: Universitat de València

Title: Genetic and other intrinsic factors influencing risk for elbow tendinopathy
Doctoral candidate: McPeek, Emily Renae
Director(s): Alakhdar Mohmara, Yasser; Alberola Aguilar, Antonio
Date of the defense: 08/03/2019
University: Universitat de València