{"id":7409,"date":"2025-04-10T09:06:31","date_gmt":"2025-04-10T09:06:31","guid":{"rendered":"https:\/\/tst.incliva.es\/?page_id=7409"},"modified":"2025-04-10T09:06:31","modified_gmt":"2025-04-10T09:06:31","slug":"research-group-on-cardiac-experimental-electrophysiology","status":"publish","type":"page","link":"https:\/\/tst.incliva.es\/en\/que-hacemos\/areas\/cardiovascular\/research-group-on-cardiac-experimental-electrophysiology\/","title":{"rendered":"Research Group on Cardiac Experimental Electrophysiology"},"content":{"rendered":"

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Research Group on Cardiac Experimental Electrophysiology<\/h3>\n<\/div>\n
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Cardiovascular Area<\/span><\/h5>\n<\/div>\n
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\n Publication of the results obtained on using the 1,4-benzothiazepine derivative JTV-519 to modify the proarrhythmogenic manifestations of mechanoelectric feedback and continuation of the programmed experimental series to analiyze the effects of KN-93, carvedilol and analogues, late Na+ current inhibitors and the Nitric Oxide carrier S-nitrosoglutathione<\/p>\n

– Continuation of the analysis of the effects of modifications of the basic electrophysiological properties on the processes involved in the induction and maintenance of ventricular fibrillation<\/p>\n

– Analysis of the electrophysiological effects of chronic physical exercise and its protective effect against arrhythmias, the influence of the cardiac nervous system and mitochondrial oxidative stress and the involvement of the IKATP current<\/p>\n

– Development of instruments for recording, processing and analysing cardiac electrophysiological signals obtained with mapping systems<\/p>\n

– Progressive development of the experimental series aimed to study the mechanisms involved in the deterioration of the systolic function, fibrosis and the inducibility of arrhythmias in a chronic model of infarction<\/p>\n

– Progressive development of an experimental model of metabolic syndrome to analyze the electrophysiological modifications and the inducibility of cardiac arrhythmias
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