Functional transcriptomic analysis of centenarians’ offspring reveals a specific genetic footprint that may explain that they are less frail than age-matched non-centenarians’ offspring. Ingles M, Belenguer-Varea A, Serna E, Mas-Bargues C, Tarazona-Santabalbina F, Borras C, Vina J. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Oct 6;77(10):1931-1938. doi: 10.1093/gerona/glac119. PMID: 35640160

Genistein effect on cognition in prodromal Alzheimer’s disease patients. The GENIAL clinical trial. Vina J, Escudero J, Baquero M, Cebrian M, Carbonell-Asins J, Munoz J, Satorres E, Melendez J, Ferrer-Rebolleda J, Cozar-Santiago M, Santabarbara-Gomez J, Jove M, Pamplona R, Tarazona-Santabalbina F, Borras C. Alzheimers Research & Therapy. 2022 Nov 4;14(1):164. doi: 10.1186/s13195-022-01097-2. PMID: 36329553

Genistein, a tool for geroscience. Bargues C, Borras C, Vina J. Mechanisms of Ageing and Development. 2022 Jun;204:111665. doi: 10.1016/j.mad.2022.111665. PMID: 35307412

Long-lived humans have a unique plasma sphingolipidome. Pradas I, Jove M, Huynh K, Ingles M, Borras C, Mota-Martorell N, Galo-Licona JD, Puig J, Vina J, Meikle PJ, Pamplona R. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2022 Apr 1;77(4):728-735. doi: 10.1093/gerona/glab360. PMID: 34871393

Oxidative stress and inflammation: from mechanisms to therapeutic approaches. Gambini J, Stromsnes K. Biomedicines. 2022 Mar 23;10(4):753. doi: 10.3390/biomedicines10040753. PMID: 35453503

Potential add-on effects of manual therapy techniques in migraine patients: a randomised controlled trial. Munoz-Gomez E, Serra-Ano P, Molla-Casanova S, Sempere-Rubio N, Aguilar-Rodriguez M, Espi-Lopez G, Ingles M. Journal of Clinical Medicine. 2022 Aug 11;11(16):4686. doi: 10.3390/jcm11164686. PMID: 36012924

Recent approaches to determine static and dynamic redox state-related parameters. Mas-Bargues C, Garcia-Dominguez E, Borras C. Antioxidants. 2022 Apr 28;11(5):864. doi: 10.3390/antiox11050864. PMID: 35624728

Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice. Sanz-Ros J, Romero-Garcia N, Mas-Bargues C, Monleon D, Gordevicius J, Brooke RT, Dromant M, Diaz A, Derevyanko A, Guio-Carrion A, Roman-Dominguez A, Ingles M, Blasco MA, Horvath S, Vina J, Borras C. Science Advances. 2022 Oct 21;8(42):eabq2226. doi: 10.1126/sciadv.abq2226. PMID: 36260670

Special issue «Oxidative stress in aging and associated chronic diseases». Mas-Bargues C, Alique M, Barrús-Ortiz MT, Borrás C, Rodrigues-Díez R. Antioxidants. 2022 Apr 2;11(4):701. doi: 10.3390/antiox11040701. PMID: 35453386

The contribution of extracellular vesicles from senescent endothelial and vascular smooth muscle cells to vascular calcification. Mas-Bargues C, Borras C, Alique M. Frontiers In Cardiovascular Medicine. 2022 Apr 15;9:854726. doi: 10.3389/fcvm.2022.854726. PMID: 35498012

The multimodal action of genistein in Alzheimer’s and other age-related diseases. Mas-Bargues C, Borras C, Vina J. Free Radical Biology & Medicine. 2022 Apr;183:127-137. doi: 10.1016/j.freeradbiomed.2022.03.021. PMID: 35346775

Therapeutic potential of extracellular vesicles in aging and age-related diseases. Sanz-Ros J, Mas-Bargues C, Romero-Garcia N, Huete-Acevedo J, Dromant M, Borras C. International Journal of Molecular Sciences. 2022 Nov 23;23(23):14632. doi: 10.3390/ijms232314632. PMID: 36498960

Transcriptomic profile of epileptic children treated with ketogenic therapies. Ruiz-Herrero J, Olaso-Gonzalez G, Serna E, Canedo-Villarroya E, Correas A, Gambini J, Gomez-Cabrera M, Pedron-Giner C, Vina J. Journal of Integrative Neuroscience. 2022 Jan 28;21(1):31. doi: 10.31083/j.jin2101031. PMID: 35164467

Biomechanical and viscoelastic properties of the ankle muscles in men with previous history of ankle sprain. Serra-Ano P, Ingles M, Espi-Lopez G, Sempere-Rubio N, Aguilar-Rodriguez M. Journal of Biomechanics. 2021 Jan 22;115:110191. doi: 10.1016/j.jbiomech.2020.110191. PMID: 33385869

Decellularized tracheal prelamination implant: A proposed bilateral double organ technique. Martinez-Hernandez N, Diaz-Cuevas A, Milian-Medina L, Sancho-Tello M, Rosello-Ferrando J, Morcillo-Aixela A, Campo-Canaveral J, Roig-Bataller A, Mata-Roig M. Artificial Organs. 2021 Dec;45(12):1491-1500. doi: 10.1111/aor.14043. PMID: 34310703

Diagnostic performance of muscle echo intensity and fractal dimension for the detection of frailty phenotype. Miron Mombiela R, Vucetic J, Monllor P, Cardenas-Herran JS, Taltavull de la Paz P, Borras C. Ultrasonic Imaging. 2021 Nov;43(6):337-352. doi: 10.1177/01617346211029656. PMID: 34238072

Domestic pig prioritized in one health action against fascioliasis in human endemic areas: Experimental assessment of transmission capacity and epidemiological evaluation of reservoir role. Mas-Coma S, Funatsu IR, Angles R, Buchon P, Mas Bargues C, Artigas P, Valero MA, Bargues MD. One Health. 2021 Apr 16;13:100249. doi: 10.1016/j.onehlt.2021.100249. PMID: 33997234

Effectiveness of a manual therapy protocol based on articulatory techniques in migraine patients. A randomized controlled trial. Munoz-Gomez E, Ingles M, Serra-Ano P, Espi-Lopez GV. Musculoskeletal Science & Practice. 2021 Apr 30;54:102386. doi: 10.1016/j.msksp.2021.102386. PMID: 33989990

Effectiveness of high-frequency transcranial magnetic stimulation and physical exercise in women with fibromyalgia: a randomized controlled trial. Izquierdo-Alventosa R, Ingles M, Cortes-Amador S, Gimeno-Mallench L, Sempere-Rubio N, Serra-Ano P. Physical Therapy & Rehabilitation Journal. 2021 Oct 1;101(10):pzab159. doi: 10.1093/ptj/pzab159. PMID: 34216139

Effects of balance training on functionality, ankle instability, and dynamic balance outcomes in people with chronic ankle instability: Systematic review and meta-analysis. Molla-Casanova S, Ingles M, Serra-Ano P. Clinical Rehabilitation. 2021 Dec;35(12):1694-1709. doi: 10.1177/02692155211022009. PMID: 34058832

Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain. A randomized controlled trial. Espí López G, Aguilar Rodríguez M, Zarzoso Muñoz M, Serra Año M, Martinez De La Fuente J, Inglés De La Torre M, Marques-Sule E. European Journal of Physical and Rehabilitation Medicine. 2021 Jun;57(3):397-405. doi: 10.23736/S1973-9087.20.06302-9. PMID: 33047944

Estrogen replacement therapy induces antioxidant and longevity-related genes in women after medically induced menopause. Borras C, Ferrando M, Ingles M, Gambini J, Lopez-Grueso R, Edo R, Mas-Bargues C, Pellicer A, Vina J. Oxidative Medicine and Cellular Longevity. 2021 Sep 9;2021:8101615. doi: 10.1155/2021/8101615. PMID: 34539974

Exploring new kingdoms: the role of extracellular vesicles in oxi-inflamm-aging related to cardiorenal syndrome. Mas-Bargues C, Alique M, Barrus-Ortiz M, Borras C, Rodrigues-Diez R. Antioxidants. 2021 Dec 29;11(1):78. doi: 10.3390/antiox11010078. PMID: 35052582

Importance of stem cell culture conditions for their derived extracellular vesicles therapeutic effect. Mas-Bargues C, Borras C. Free Radical Biology & Medicine. 2021 May 20;168:16-24. doi: 10.1016/j.freeradbiomed.2021.03.028. PMID: 33781893

Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus. Borras C, Abdelaziz KM, Diaz A, Gambini J, Jove M, Lopez-Grueso R, Mas-Bargues C, Monleon D, Pamplona R, Vina J. Mechanisms of Ageing and Development. 2021 Dec;200:111596. doi: 10.1016/j.mad.2021.111596. PMID: 34774606

Lipid peroxidation as measured by chromatographic determination of malondialdehyde. Human plasma reference values in health and disease. Mas-Bargues C, Escrivá C, Dromant M, Borrás C, Viña J. Archives of Biochemistry and Biophysics. 2021 Sep 30;709:108941. doi: 10.1016/j.abb.2021.108941. PMID: 34097903

Moderate Red Wine Consumption Increases the Expression of Longevity-Associated Genes in Controlled Human Populations and Extends Lifespan in Drosophila melanogaster. Gambini J, Gimeno-Mallench L, Olaso-Gonzalez G, Mastaloudis A, Traber M, Monleon D, Borras C, Vina J. Antioxidants. 2021 Feb 16;10(2):301. doi: 10.3390/antiox10020301. PMID: 33669360

Pharmacological properties of polyphenols: bioavailability, mechanisms of action, and biological effects in in vitro studies, animal models, and humans. Stromsnes K, Lagzdina R, Olaso-Gonzalez G, Gimeno-Mallench L, Gambini J. Biomedicines. 2021 Aug 23;9(8):1074. doi: 10.3390/biomedicines9081074. PMID: 34440278

Role of antiangiogenic VEGF-A165b in angiogenesis and systolic function after reperfused myocardial infarction. Rios Navarro C, Hueso Soler L, Diaz Cuevas A, Marcos Garcés V, Bonanad Lozano C, Ruiz Sauri A, Vila Salinas J, Sanz Ferrando M, Chorro Gascó F, Piqueras Ruiz L, Bodí Peris V. Revista espanola de Cardiologia (English ed.). 2021 Feb;74(2):131-139. doi: 10.1016/j.rec.2020.03.013. PMID: 32474003

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates. Duro-Castano A, Borras C, Herranz-Perez V, Blanco-Gandia M, Conejos-Sanchez I, Arminan A, Mas-Bargues C, Ingles M, Minarro J, Rodriguez-Arias M, Garcia-Verdugo J, Vina J, Vicent M. Science Advances. 2021 Mar 26;7(13):eabf9180. doi: 10.1126/sciadv.abf9180. PMID: 33771874

Thermal imaging ruled out as a supplementary assessment in patients with fibromyalgia: a cross-sectional study. Sempere-Rubio N, Aguilar-Rodriguez M, Ingles M, Izquierdo-Alventosa R, Serra-Ano P. PLoS One. 2021 Jun 16;16(6):e0253281. doi: 10.1371/journal.pone.0253281. PMID: 34133467

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. NCD Risk Factor Collaboration. Lancet. 2021 Sep 11;398(10304):957-980. doi: 10.1016/S0140-6736(21)01330-1. PMID: 34450083

Donkey fascioliasis within a one health control action: transmission capacity, field epidemiology, and reservoir role in a human hyperendemic área. Mas-Coma S, Buchon P, Funatsu I, Angles R, Mas Bargues C, Artigas P, Valero M, Bargues M. Frontiers in Veterinary Science. 2020 Nov 5;7:591384. doi: 10.3389/fvets.2020.591384. PMID: 33251272

Effect of manual therapy and splint therapy in people with temporomandibular disorders: a preliminary study. Espí López G, Arnal-Gomez A, Cuerda Del Pino A, Benavent-Corai J, Serra Año M, Inglés De La Torre M. Journal of Clinical Medicine. 2020 Jul 28;9(8):2411. doi: 10.3390/jcm9082411. PMID: 32731453

Extracellular vesicles and redox modulation in aging. Borras Blasco C, Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Gambini Buchon J, Viña Ribes J. Free Radical Biology and Medicine. 2020 Mar;149:44-50. doi: 10.1016/j.freeradbiomed.2019.11.032. PMID: 31783096

Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1alpha Activation. Mas Bargues C, Sanz Ros J, Román Domínguez M, Gimeno Mallench L, Inglés De La Torre M, Viña Ribes J, Borras Blasco C. Biomolecules. 2020 Jun 25;10(6):957. doi: 10.3390/biom10060957. PMID: 32630449

Garcinoic acid prevents beta-amyloid (Abeta) deposition in the mouse brain. Marinelli R, Torquato P, Bartolini D, Mas Bargues C, Bellezza G, Gioiello A, Borras Blasco C, De Luca A, Fallarino F, Sebastiani B, Mani S, Sidoni A, Viña Ribes J, Leri M, Bucciantini M, Nardiello P, Casamenti F, Galli F. Journal of biological chemistry. 2020 Aug 14;295(33):11866-11876. doi: 10.1074/jbc.RA120.013303. PMID: 32616652

Low-Intensity Physical Exercise Improves Pain Catastrophizing and Other Psychological and Physical Aspects in Women with Fibromyalgia: A Randomized Controlled Trial. Izquierdo-Alventosa R, Inglés De La Torre M, Cortes-Amador S, Gimeno Mallench L, Chirivella-Garrido J, Kropotov J, Serra Año M. International Journal of Environmental Research and Public Health. 2020 May 21;17(10):3634. doi: 10.3390/ijerph17103634. PMID: 32455853

Methionine transsulfuration pathway is upregulated in long-lived humans. Mota-Martorell N, Mariona J, Consuelo B, Rebeca B, Elia O, Joaquim S, Rosanna C, Irene P, Galo-Licona J, Josep P, Jose V, Reinald P. Free Radical Biology & Medicine. 2020 Nov 30;162:38-52. doi: 10.1016/j.freeradbiomed.2020.11.026. PMID: 33271279

Numerous Fasciola plasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis (vol 146, pg 284, 2019). Gonzalez-Miguel J, Valero M, Reguera-Gomez M, Mas Bargues C, Bargues M, Simon-Martin F, Mas-Coma S. Parasitology. 2020 May;147(6):729. doi: 10.1017/S0031182020000268. PMID: 32052717

Oxidative stress and exceptional human longevity: Systematic review. Belenguer-Varea A, Tarazona-Santabalbina F, Avellana-Zaragoza J, Martinez-Reig M, Mas Bargues C, Inglés De La Torre M. Free Radical Biology and Medicine. 2020 Mar;149:51-63. doi: 10.1016/j.freeradbiomed.2019.09.019. PMID: 31550529

Paths of the cervical instantaneous axis of rotation during active movements-patterns and reliability.Venegas W, Inglés De La Torre M, Page A, Serra-Ano P. Medical & Biological Engineering & Computing. 2020 May;58(5):1147-1157. doi: 10.1007/s11517-020-02153-5. PMID: 32193862

Protective Effects of Polyphenols Present in Mediterranean Diet on Endothelial Dysfunction. Stromsnes K, Mas-Bargues C, Gambini J, Gimeno-Mallench L. Oxidative medicine and cellular longevity. 2020 Aug 6;2020:2097096. doi: 10.1155/2020/2097096. PMID: 32831990

Relationship between Diet, Microbiota, and Healthy Aging. Sanchez-Morate E, Gimeno Mallench L, Stromsnes K, Sanz Ros J, Roman-Dominguez A, Parejo-Pedrajas S, Inglés De La Torre M, Olaso González G, Gambini Buchon J, Mas Bargues C. Biomedicines. 2020 Aug 14;8(8):287. doi: 10.3390/biomedicines8080287. PMID: 32823858

Special issue: Redox Signalling in Health and Disease. Borras Blasco C, Viña Ribes J. Free Radical Biology And Medicine. 2020 Mar;149:1. doi: 10.1016/j.freeradbiomed.2020.02.009. PMID: 32061736

The Relationship between Diet and Frailty in Aging. Gimeno Mallench L, Sanchez-Morate E, Parejo-Pedrajas S, Mas Bargues C, Inglés De La Torre M, Sanz Ros J, Roman-Dominguez A, Olaso González G, Stromsnes K, Gambini Buchon J. Endocrine, Metabolic & Immune Disorders Drug Targets. 2020;20(9):1373-1382. doi: 10.2174/1871530320666200513083212. PMID: 32400339