Clinical Associated Group in Traumatology and Orthopedics

Associated Clinical Group

Non-invasive imaging in orthopedics

New prosthesis fixation systems applied to Traumatology

Mechanisms of inflammation and oxidative stress in bone pathologies

Coordinator
Dr. Antonio Silvestre Muñoz
antonio.silvestre@uv.es

RESEARCHERS
Leading, R4

Antonio Silvestre Muñoz    

Established, R3

Pablo Renovell Ferrer
Rosa María Cibrián Ortiz de Anda

Recognised/Emerging, R2

José Albelda Vitoria
Laura Pino Almero
Rosario Salvador Palmer

First Stage, R1
STAFF
Collaborating Researchers

José Expósito Ollero

Nurse
Technicians
Administrative assistant
Publications
New insights into the pro-inflammatory and osteoclastogenic profile of circulating monocytes in osteoarthritis patients. Guillem-Llobat P, Marín M, Rouleau M, Silvestre A, Blin-Wakkach C, Ferrándiz M, Guillén M, Ibáñez L. International Journal of Molecular Sciences. 2024 Jan 30;25(3):1710. doi: 10.3390/ijms25031710. PMID: 38338988

A comparative analysis of mathematical methods for detecting lactate thresholds using muscle oxygenation data during a graded cycling test. Sendra-Perez C, Encarnacion-Martinez A, Oficial-Casado F, Salvador-Palmer R, Priego Quesada J. Physiological Measurement. 2023 Dec 11. doi: 10.1088/1361-6579/ad1457. PMID: 38081136

Acute effects of in-hospital resistance training on clinical outcomes in patients undergoing total knee arthroplasty: a randomized controlled trial. Nunez-Cortes R, Lopez-Bueno L, Lopez-Bueno R, Cuenca-Martinez F, Suso-Marti L, Silvestre A, Casana J, Cruz-Montecinos C, Andersen L, Calatayud J. American Journal of Physical Medicine & Rehabilitation. 2023 Nov 22. doi: 10.1097/PHM.0000000000002366. PMID: 38063321

Application of machine learning algorithms in thermal images for an automatic classification of lumbar sympathetic blocks. Canada-Soriano M, Bovaira M, Garcia-Vitoria C, Salvador-Palmer R, de Anda R, Moratal D, Priego-Quesada J. Journal of Thermal Biology. 2023 Apr;113:103523. doi: 10.1016/j.jtherbio.2023.103523. PMID: 37055127

Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal gamma radiation. Obrador E, Salvador-Palmer R, Pellicer B, Lopez-Blanch R, Sirerol J, Villaescusa J, Montoro A, Dellinger R, Estrela J. Journal of Advanced Research. 2023 Mar;45:73-86. doi: 10.1016/j.jare.2022.05.005. PMID: 35599107

Externally applied electromagnetic fields and hyperthermia irreversibly damage cancer cells. Obrador E, Jihad-Jebbar A, Salvador-Palmer R, Lopez-Blanch R, Oriol-Caballo M, Moreno-Murciano MPaz, Navarro EA, Cibrian R, Estrela JM. Cancers. 2023 Jun 29;15(13):3413. doi: 10.3390/cancers15133413. PMID: 37444524

Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice. López-Blanch R, Salvador-Palmer R, Oriol-Caballo M, Moreno-Murciano P, Dellinger RW, Estrela JM, Obrador E. Neurotherapeutics. 2023 Dec 19;21(1):e00301. doi: 10.1016/j.neurot.2023.10.011. PMID: 38241160

Reliability of threshold determination using portable muscle oxygenation monitors during exercise testing: a systematic review and meta-analysis. Sendra-Perez C, Sanchez-Jimenez J, Marzano-Felisatti J, Encarnacion-Martinez A, Salvador-Palmer R, Priego-Quesada J. Scientific Reports. 2023 Aug 4;13(1):12649. doi: 10.1038/s41598-023-39651-z. PMID: 37542055

Sex-related differences in profiles of muscle oxygen saturation of different muscles in trained cyclists during graded cycling exercise. Sendra-Perez C, Priego-Quesada J, Salvador Palmer R, Murias J, Encarnacion-Martinez A. Journal of Applied Physiology. 2023 Nov 1;135(5):1092-1101. doi: 10.1152/japplphysiol.00420.2023. PMID: 37732376

Survival mechanisms of metastatic melanoma cells: the link between glucocorticoids and the Nrf2-dependent antioxidant defense system. Obrador E, Salvador-Palmer R, Lopez-Blanch R, Oriol-Caballo M, Moreno-Murciano P, Estrela J. Cells. 2023 Jan 26;12(3):418. doi: 10.3390/cells12030418. PMID: 36766760

Association between malocclusion and articulation of phonemes in early childhood. Amr-Rey O, Sanchez-Delgado P, Salvador-Palmer R, Cibrian R, Paredes-Gallardo V. The Angle Orthodontist. 2022 Jul 1;92(4):505-511. doi: 10.2319/043021-342.1. PMID: 35275982

Chronic and acute effects on skin temperature from a sport consisting of repetitive impacts from hitting a ball with the hands. Sanchez-Jimenez J, Tejero-Pastor R, Calzadillas-Valles M, Jimenez-Perez I, de Anda R, Salvador-Palmer R, Priego-Quesada J. Sensors. 2022 Nov 7;22(21):8572. doi: 10.3390/s22218572. PMID: 36366270

Effect of 10 km run on lower limb skin temperature and thermal response after a cold-stress test over the following 24 h. Priego-Quesada J, Catala-Vilaplana I, Bermejo-Ruiz J, Gandia-Soriano A, Pellicer-Chenoll M, Encarnacion-Martinez A, Cibrian Ortiz de Anda R, Salvador-Palmer R. Journal of Thermal Biology. 2022 Apr;105:103225. doi: 10.1016/j.jtherbio.2022.103225. PMID: 35393059

Effects of squatting with elastic bands or conventional resistance-training equipment at different effort levels in post-exercise intraocular pressure of healthy men. Gene-Morales J, Gene-Sampedro A, Salvador-Palmer R, Colado JC. Biology of Sport. 2022 Oct;39(4):895-903. doi: 10.5114/biolsport.2022.109955. PMID: 36247937

Fall classification, incidence and circumstances in patients undergoing total knee replacement. Blasco J, Perez-Maletzki J, Diaz-Diaz B, Silvestre-Munoz A, Martinez-Garrido I, Roig-Casasus S. Scientific Reports. 2022 Nov 18;12(1):19839. doi: 10.1038/s41598-022-23258-x. PMID: 36400816

Impact of the COVID-19 pandemic on a cancer fast-track programme. Martinez M, Moragon S, Ortega-Morillo B, Monton-Bueno J, Simon S, Rosello S, Insa A, Viala A, Navarro J, Sanmartin A, Fluixa C, Julve A, Soriano D, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner M, Cano A, Silvestre A, Teruel A, Bermejo B, Cervantes A, Chirivella Gonzalez I. Cancer Control. 2022 Jan-Dec;29:10732748221131000. doi: 10.1177/10732748221131000. PMID: 36355430

N-Acetylcysteine promotes metastatic spread of melanoma in mice. Obrador E, Salvador-Palmer R, Lopez-Blanch R, Oriol-Caballo M, Moreno-Murciano P, Estrela J. Cancers. 2022 Jul 25;14(15):3614. doi: 10.3390/cancers14153614. PMID: 35892873

Sigmoid volvulus. Moro-Valdezate D, Martín-Arévalo J, Pla-Martí V, García-Botello S, Izquierdo-Moreno A, Pérez-Santiago L, Pedrós-Giménez JM, Villagrasa R, Peña A, Espí-Macías A. Langenbeck’s archives of surgery. 2022 May;407(3):1161-1171. doi: 10.1007/s00423-022-02428-5. PMID: 35028738

Skin temperature measurement in individuals with spinal cord injury during and after exercise: Systematic review. Sanchez-Jimenez JL, Aparicio I, Romero-Avila JL, Bellot-Arcís C, Cibrián Ortiz de Anda RM, Priego-Quesada JI. Journal of Thermal Biology. 2022 Apr;105:103146. doi: 10.1016/j.jtherbio.2021.103146. PMID: 35393040

Treatment patterns and intensification within 5 year of follow-up of the first-line anti-TNFα used for the treatment of IBD: Results from the VERNE study. Bastida G, Marin-Jimenez I, Fores A, Garcia-Planella E, Arguelles-Arias F, Tagarro I, Fernandez-Nistal A, Montoto C, Aparicio J, Aguas M, Santos-Fernandez J, Bosca-Watts M, Ferreiro-Iglesias R, Merino O, Aldeguer X, Cortes X, Sicilia B, Mesonero F, Barreiro-de Acosta M. Digestive and liver disease. 2022 Jan;54(1):76-83. doi: 10.1016/j.dld.2021.06.005. PMID: 34244110

A randomized controlled trial assessing the effects of preoperative strengthening plus balance training on balance and functional outcome up to 1 year following total knee replacement. Dominguez-Navarro F, Silvestre Muñoz A, Igual-Camacho C, Diaz-Diaz B, Torrella J, Rodrigo J, Paya Rubio A, Roig-Casasus S, Blasco J. Knee Surgery Sports Traumatology Arthroscopy. 2021 Mar;29(3):838-848. doi: 10.1007/s00167-020-06029-x. PMID: 32342139

A solitary osteochondroma of the scapula: uncommon location for a common tumor. Sancheza D, Almero L, Rey M. Archivos Argentinos de Pediatria. 2021 Oct;119(5):e562-e566. doi: 10.5546/aap.2021.e562. PMID: 34569764

Improving the cementation of the tibial component in knee arthroplasty: a study of four techniques in the cadaver. Rodriguez-Collell J, Mifsut D, Ruiz-Sauri A, Rodriguez-Pino L, Gonzalez-Soler E, Valverde-Navarro A. Bone & Joint Research. 2021 Aug;10(8):467-473. doi: 10.1302/2046-3758.108.BJR-2020-0524.R1. PMID: 34340533

Osteosarcoma of the Trapezium. Ferrando E, Navarro J, Rojas R, Mata D, Silvestre A. Journal of Hand Surgery. 2021 Aug;46(8):717.e1-717.e5. doi: 10.1016/j.jhsa.2020.10.011. PMID: 33277099

Ten-year assessment of a cancer fast-track programme to connect primary care with oncology: reducing time from initial symptoms to diagnosis and treatment initiation. Martinez MT, Monton-Bueno J, Simon S, Ortega B, Moragon S, Rosello S, Insa A, Navarro J, Sanmartin A, Julve A, Buch E, Pena A, Franco J, Martinez-Jabaloyas J, Marco J, Forner MJ, Cano A, Silvestre A, Teruel A, Lluch A, Cervantes A, Chirivella Gonzalez I. ESMO open. 2021 May 11;6(3):100148. doi: 10.1016/j.esmoop.2021.100148. PMID: 33989988

Projects
Reference: DTS18/00177
Title: Desarrollo de un nuevo sistema de fijación intramedular para implantes (prótesis, clavos para fracturas y exoprótesis).
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Antonio Silvestre Muñoz
Duration: 2019 – 2021
Total budget: 99.550 €
+ Info
Title: Creación de un instrumento de decisión objetivo para la indicación de tratamiento quirúrgico versus conservador en la fractura de cadera
Doctoral candidate: Orts Garcia, Eduardo Javier
Director(s): Avellana Zaragoza, Juan Antonio; Silvestre Muñoz, Antonio; Gomar Sancho, Francisco
Date of the defense: 16/05/2023
University: Universitat de València

Title: Utilización de cótilos de doble movilidad en cirugía protésica de cadera ¿pueden mejorar los óptimos resultados?
Doctoral candidate: Hernández Ferrando, Lorenzo José
Director(s): Silvestre Muñoz, Antonio
Date of the defense: 25/11/2022
University: Universitat de València

Title: The potential of elastic bands to optimize ocular and cardiovascular responses, subjective effort, and performance in squats
Doctoral candidate: Gené Morales, Javier
Director(s): Salvador Palmer, María Rosario; Gené Sampedro, Andrés; Colado Sánchez, Juan Carlos
Date of the defense: 07/04/2022
University: Universitat de València

Title: Análisis de la marcha en pacientes con pie zambo tratados mediante el método de ponseti frente a la técnica quirúrgica de liberación posterior
Doctoral candidate: Ferrando De Jorge, Albert
Director(s): Page Del Pozo, Álvaro Felipe; Atienza Vicente, Carlos Manuel; Salom Taverner, Marta; Mínguez Rey, M. Fe
Date of the defense: 28/03/2019
University: Universitat de València

Title: Comparativa de los resultados clínicos y biomecánicos del tratamiento de la patología de la porción larga del bíceps braquial: tenotomía o tenodesis
Doctoral candidate: García Rellán, José Emmanuel
Director(s): Gomar Sancho, Francisco
Date of the defense: 09/03/2019
University: Universitat de València