Dr. Carlos Solano Vercet

Principal Investigator
Research Group on Hematopoietic Transplantation

Presentation

Principal
Investigator
Dr. Carlos Solano Vercet

carlos.solano@uv.es

Publications
Graft-versus-host-disease prophylaxis with ATG or PTCY in patients with lymphoproliferative disorders undergoing reduced intensity conditioning regimen HCT from one antigen mismatched unrelated donor. Paviglianiti A, Ngoya M, Pena M, Boumendil A, Guelbas Z, Ciceri F, Bonifazi F, Russo D, Fegueux N, Stolzel F, Bulabois C, Socie G, Forcade E, Solano C, Finel H, Robinson S, Glass B, Montoto S. Bone Marrow Transplantation. 2024 Feb 8. doi: 10.1038/s41409-024-02225-2. PMID: 38331980

Prophylaxis and management of graft-versus-host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation. Penack O, Marchetti M, Aljurf M, Arat M, Bonifazi F, Duarte R, Giebel S, Greinix H, Hazenberg M, Kroger N, Mielke S, Mohty M, Nagler A, Passweg J, Patriarca F, Ruutu T, Schoemans H, Solano C, Vrhovac R, Wolff D, Zeiser R, Sureda A, Peric Z. Lancet. Haematology. 2024 Jan 3:S2352-3026(23)00342-3. doi: 10.1016/S2352-3026(23)00342-3. PMID: 38184001

Upper and/or lower respiratory tract infection caused by human metapneumovirus after allogeneic hematopoietic stem cell transplantation. Piñana JL, Tridello G, Xhaard A, Wendel L, Montoro J, Vazquez L, Heras I, Ljungman P, Mikulska M, Salmenniemi U, Perez A, Kröger N, Cornelissen JJ, Sala E, Martino R, Geurten C, Byrne J, Maertens J, Kerre T, Martin M, Pascual MJ, Yeshurun M, Finke J, Groll AH, Shaw PJ, Blijlevens N, Arcese W, Ganser A, Suarez-Lledo M, Alzahrani M, Choi G, Forcade E, Paviglianiti A, Solano C, Wachowiak J, Zuckerman T, Bader P, Clausen J, Mayer J, Schroyens W, Metafuni E, Knelange N, Averbuch D, de la Camara R. The Journal of Infectious Diseases. 2024 Jan 12;229(1):83-94. doi: 10.1093/infdis/jiad268. PMID: 37440459

Assessment of the potential value of plasma Torque Teno virus DNA load monitoring to predict cytomegalovirus DNAemia in patients with hematological malignancies treated with small molecule inhibitors: a proof-of-concept study. de la Asunción C, Giménez E, Hernández-Boluda J, Terol M, Albert E, López J, García-Gutiérrez V, Andreu R, Malo M, Fox M, Remigia M, Amat P, Solano C, Navarro D. Journal of Medical Virology. 2023 Jul;95(7):e28933. doi: 10.1002/jmv.28933. PMID: 37403897

Cytomegalovirus DNAemia in hematological patients undergoing CD19-directed CAR-T cell therapy: should it be systematically monitored?. Solano de la Asuncion C, Hernani R, Albert E, Gomez M, Gimenez E, Benzaquen A, Gonzalez-Barbera E, Hernandez-Boluda J, Perez A, Pinana J, Chorao P, Guerreiro M, Montoro J, Sanz J, Solano C, Navarro D. Clinical Microbiology and Infection. 2023 Aug;29(8):1093-1095. doi: 10.1016/j.cmi.2023.05.010. PMID: 37182642

Features of cytomegalovirus DNAemia and virus-specific T-cell responses in allogeneic hematopoietic stem-cell transplant recipients during prophylaxis with letermovir. Gimenez E, Guerreiro M, Torres I, Aguilar C, Albert E, Hernandez-Boluda JC, Hernani R, Perez A, Amat P, Pinana JL, Montoro J, Solano C, Navarro D. Transplant Infectious Disease. 2023 Apr;25(2):e14021. doi: 10.1111/tid.14021. PMID: 36748748

Immunobiology of cytomegalovirus infection in patients with haematological malignancies undergoing treatment with small molecule inhibitors. Solano De la Asuncion C, Gimenez E, Hernandez-Boluda JC, Terol MJ, Albert E, Lopez-Jimenez J, Garcia-Gutierrez V, Andreu R, Garcia D, Fox ML, Remigia MJ, Amat P, Solano C, Navarro D. British Journal of Haematology. 2023 Mar;200(6):e58-e61. doi: 10.1111/bjh.18655. PMID: 36652997

Immunovirology of cytomegalovirus infection in allogeneic stem cell transplant recipients undergoing prophylaxis with letermovir: a narrative review. Solano C, Giménez E, Albert E, Piñana J, Navarro D. Journal of Medical Virology. 2023 Aug;95(8):e29005. doi: 10.1002/jmv.29005. PMID: 37526411

Impact of cytomegalovirus immunodominant HLA-I donor-recipient matching on the incidence and features of virus DNAemia and virus-specific T-cell immune reconstitution in unmanipulated haploidentical hematopoietic stem cell transplantation. Huntley D, Gimenez E, Vazquez L, Pascual M, Amat P, Remigia M, Hernandez-Boluda J, Garcia M, Gago B, Torres I, de la Asuncion C, Hernani R, Perez A, Albert E, Pinana J, Solano C, Navarro D. Transplant Infectious Disease. 2023 Jun;25(3):e14065. doi: 10.1111/tid.14065. PMID: 37120821

Improved outcomes over time and higher mortality in CMV seropositive allogeneic stem cell transplantation patients with COVID-19; An infectious disease working party study from the European Society for Blood and Marrow Transplantation registry. Ljungman P, Tridello G, Pinana J, Ciceri F, Sengeloev H, Kulagin A, Mielke S, Yegin Z, Collin M, Einardottir S, Lepretre S, Maertens J, Campos A, Metafuni E, Pichler H, Folber F, Solano C, Nicholson E, Yuksel M, Carlson K, Aguado B, Besley C, Byrne J, Heras I, Dignan F, Kroger N, Robin C, Khan A, Lenhoff S, Grassi A, Dobsinska V, Miranda N, Jimenez M, Yonal-Hindilerden I, Wilson K, Averbuch D, Cesaro S, Xhaard A, Knelange N, Styczynski J, Mikulska M, de la Camara R. Frontiers in Immunology. 2023 Mar 7;14:1125824. doi: 10.3389/fimmu.2023.1125824. PMID: 36960069

In vitro assessment of the combined effect of letermovir and sirolimus on cytomegalovirus replication. Gimenez E, Guerreiro M, Gozalbo-Rovira R, Aguilar C, Albert E, Pinana J, Solano C, Navarro D. Revista Espanola de Quimioterapia. 2023 Oct;36(5):526-530. doi: 10.37201/req/016.2023. PMID: 37365797

Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion. Martin Castillo I, Villamon Ribate E, Calabuig Munoz M, Sanz Santillana G, Such Taboada E, Mora Castera E, Calasanz Abinzano MJ, Irigoyen Barranco A, Collado Nieto R, Vara Pampliega M, Blanco ML, Alvarez de Andres S, Perez de Oteyza J, Bernal del Castillo T, Granada Font I, Jerez Cayuela A, Diez-Campelo M, Abellan Sanchez R.; Solano Vercet C, Tormo Diaz M. Cancer Medicine. 2023 Aug;12(16):16788-16792. doi: 10.1002/cam4.6300. PMID: 37403747

Monitoring for virus-specific T-cell responses and viremia in allogeneic HSCT recipients: a survey from the EBMT Cellular Therapy & Immunobiology Working Party. Greco R, Hoogenboom JD, Bonneville EF, Anagnostopoulos A, Cuoghi A, Dalle JH, Weissinger EM, Lang P, Galaverna F, Martino M, Maschan A, Mauz-Korholz C, Noviello M, Passweg J, Peccatori J, Rovira M, Solano C, Veelken H, Velardi A, Wagner-Drouet EM, Zhang X, Ciceri F, Bonini C, Vago L, Ruggeri A, Chabannon C. Bone Marrow Transplantation. 2023 May;58(5):603-606. doi: 10.1038/s41409-023-01939-z. PMID: 36813866

Monitoring of plasma Torque teno virus, total Anelloviridae and Human Pegivirus 1 viral load for the prediction of infectious events and acute graft versus host disease in the allogeneic hematopoietic stem cell transplantation setting. Forqué L, Albert E, Piñana JL, Pérez A, Hernani R, Solano C, Navarro D, Giménez E. Journal of Medical Virology. 2023 Sep;95(9):e29107. doi: 10.1002/jmv.29107. PMID: 37721473

One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients. Pinana JL, Vazquez L, Calabuig M, Lopez-Corral L, Martin-Martin G, Villalon L, Sanz-Linares G, Conesa-Garcia V, Sanchez-Salinas A, Gago B, Facal A, Risco-Galvez I, Olave MT, Espigado I, Lopez-Jimenez J, Hernandez-Rivas JA, Avendano-Pita A, Arroyo I, Ferrer E, Garcia-Cadenas I, Gonzalez-Santillana C, Roldan-Perez A, Ferrer B, Guerreiro M, Suarez-Lledo M, Camara A, Campos-Beltran D, Navarro D, Cedillo A, Sureda A, Solano C, Martino R. Blood Cancer Journal. 2023 Jan 5;13(1):8. doi: 10.1038/s41408-022-00778-3. PMID: 36599843

Post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis in HLA-matched and haploidentical donor transplants for patients with Hodgkin lymphoma: a comparative study of the LWP EBMT.: GVHD prophylaxis for patients with Hodgkin lymphoma. Montoro J, Boumendil A, Finel H, Bramanti S, Castagna L, Blaise D, Dominietto A, Kulagin A, Yakoub-Agha I, Tbakhi A, Solano C, Giebel S, Gulbas Z, López Corral L, Pérez-Simón JA, Díez Martín JL, Sanz J, Farina L, Koc Y, Socié G, Arat M, Jurado M, Bermudez A, Labussière-Wallet H, Villalba M, Ciceri F, Martinez C, Nagler A, Sureda A, Glass B. Transplantation and Cellular Therapy. 2023 Dec 1:S2666-6367(23)01710-4. doi: 10.1016/j.jtct.2023.11.021. PMID: 38043802

Quantifying the available capacity and resource needs for provision of CAR-T therapies in the National Health Service in Spain: a survey-based study. Solano C, Castro-Rebollo P, Perez-Martinez A, López-Corral L, Barba-Suñol P, Kwon M, Ortiz V, Sanz-Caballer J, Caballero A, Martinez J, Cedillo A, Sureda A. BMJ Open. 2023 Jul 25;13(7):e071371. doi: 10.1136/bmjopen-2022-071371. PMID: 37491085

Rationale for combined therapies in severe-to-critical COVID-19 patients. Gonzaga A, Andreu E, Hernández-Blasco L, Meseguer R, Al-Akioui-Sanz K, Soria-Juan B, Sanjuan-Gimenez J, Ferreras C, Tejedo J, Lopez-Lluch G, Goterris R, Maciá L, Sempere-Ortells J, Hmadcha A, Borobia A, Vicario J, Bonora A, Aguilar-Gallardo C, Poveda J, Arbona C, Alenda C, Tarín F, Marco F, Merino E, Jaime F, Ferreres J, Figueira J, Cañada-Illana C, Querol S, Guerreiro M, Eguizabal C, Martin-Quirós A, Robles-Marhuenda A, Pérez-Martínez A, Solano C, Soria B. Frontiers in Immunology. 2023 Sep 11:14:1232472. doi: 10.3389/fimmu.2023.1232472. PMID: 37767093

Recommendations on the use of azole antifungals in hematology-oncology patients. Azanza J, Mensa J, Barberan J, Vazquez L, Perez de Oteyza J, Kwon M, Yanez L, Aguado J, Cubillo Gracian A, Ruiz Camps I, Fortun J, Salavert Lleti M, Gudiol C, Olave Rubio T, Solano C, Garcia-Vidal C, Rovira Tarrats M, Suarez-Lledo Grande M, Gonzalez-Sierra P, Duenas Gutierrez C. Revista Espanola de Quimioterapia. 2023 Jun;36(3):236-258. doi: 10.37201/req/013.2023. PMID: 37017117

Remdesivir or nirmatrelvir/ritonavir therapy for omicron SARS-CoV-2 infection in hematological patients and cell therapy recipients. Piñana J, Heras I, Aiello T, García-Cadenas I, Vazquez L, Lopez-Jimenez J, Chorao P, Aroca C, García-Vidal C, Arroyo I, Soler-Espejo E, López-Corral L, Avendaño-Pita A, Arrufat A, Garcia-Gutierrez V, Arellano E, Hernández-Medina L, González-Santillana C, Morell J, Hernández-Rivas J, Rodriguez-Galvez P, Mico-Cerdá M, Guerreiro M, Campos D, Navarro D, Cedillo A, Martino R, Solano C. Viruses. 2023 Oct 8;15(10):2066. doi: 10.3390/v15102066. PMID: 37896843

Respiratory virus infections after allogeneic stem cell transplantation: Current understanding, knowledge gaps, and recent advances. Pinana J, Perez A, Chorao P, Guerreiro M, Garcia-Cadenas I, Solano C, Martino R, Navarro D. Transplant Infectious Disease. 2023 Nov:25 Suppl 1:e14117. doi: 10.1111/tid.14117. PMID: 37585370

Results of phase 2 randomized multi-center study to evaluate the safety and efficacy of infusion of memory T cells as adoptive therapy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia and/or lymphopenia (RELEASE NCT04578210). Ferreras C, Hernández-Blanco C, Martín-Quirós A, Al-Akioui-Sanz K, Mora-Rillo M, Ibáñez F, Díaz-Almirón M, Cano-Ochando J, Lozano-Ojalvo D, Jiménez-González M, Goterris R, Sánchez-Zapardiel E, de Paz R, Guerra-García P, Queiruga-Parada J, Molina P, Briones ML, Ruz-Caracuel B, Borobia AM, Carcas AJ, Planelles D, Vicario JL, Moreno MÁ, Balas A, Llano M, Llorente A, Del Balzo Á, Cañada C, García MÁ, Calvin ME, Arenas I, Pérez de Diego R, Eguizábal C, Soria B, Solano C, Pérez-Martínez A. Cytotherapy. 2023 Oct 29:S1465-3249(23)01056-3. doi: 10.1016/j.jcyt.2023.10.002. PMID: 37897472

SARS-CoV-2-reactive antibody waning, booster effect and breakthrough SARS-CoV-2 infection in hematopoietic stem cell transplant and cell therapy recipients at one year after vaccination. Pinana J, Martino R, Vazquez L, Lopez-Corral L, Perez A, Chorao P, Avendano Pita A, Pascual M, Sanchez Salinas A, Sanz Linares G, Olave M, Arroyo I, Tormo M, Villalon L, Conesa Garcia V, Gago B, Terol M, Villalba M, Garcia Gutierrez V, Cabero A, Hernandez Rivas J, Ferrer E, Garcia Cadenas I, Teruel A, Navarro D, Cedillo A, Sureda A, Solano C. Bone Marrow Transplantation. 2023 Feb 28;1-14. doi: 10.1038/s41409-023-01946-0. PMID: 36854892

Torque Teno Virus plasma DNA load: a novel prognostic biomarker in CAR-T therapy. Benzaquén A, Giménez E, Iacoboni G, Guerreiro M, Hernani R, Albert E, Carpio C, Balaguer A, Pérez A, S de la Asunción C, Sánchez-Salinas MA, Chorão P, Piñana JL, Beas F, Montoro J, Hernández-Boluda JC, Facal A, Ferrer B, Villalba M, Amat P, Goméz MD, Campos D, Terol MJ, Sanz J, Barba P, Navarro D, Solano C. Bone Marrow Transplantation. 2023 Nov 2. doi: 10.1038/s41409-023-02114-0. PMID: 37919456

Treatment for first cytomegalovirus infection post-hematopoietic cell transplant in the AURORA Trial: a multicenter, double-blind, randomized, phase 3 trial comparing maribavir with valganciclovir. Papanicolaou GA, Avery RK, Cordonnier C, Duarte RF, Haider S, Maertens J, Peggs KS, Solano C, Young JH, Fournier M, Murray RA, Wu J, Winston DJ; AURORA Trial Investigators. Clinical Infectious Diseases. 2023 Nov 30:ciad709. doi: 10.1093/cid/ciad709. PMID: 38036487

Allogeneic stem cell transplantation in mantle cell lymphoma; insights into its potential role in the era of new immunotherapeutic and targeted therapies: the GETH/GELTAMO experience. Gutierrez A, Bento L, Novelli S, Martin A, Gutierrez G, Salas M, Bastos-Oreiro M, Perez A, Hernani R, Viguria M, Lopez-Godino O, Montoro J, Pinana J, Ferra C, Parody R, Martin C, Espanol I, Yanez L, Rodriguez G, Zanabili J, Herrera P, Varela M, Sampol A, Solano C, Caballero D. Cancers. 2022 May 27;14(11):2673. doi: 10.3390/cancers14112673. PMID: 35681653

Applicability of probabilistic graphical models for early detection of SARS-CoV-2 reactive antibodies after SARS-CoV-2 vaccination in hematological patients. Pinana J, Rodriguez-Belenguer P, Caballero D, Martino R, Lopez-Corral L, Terol M, Vazquez L, Calabuig M, Sanz-Linares G, Marin-Jimenez F, Alonso C, Montoro J, Ferrer E, Facal A, Pascual M, Rodriguez-Fernandez A, Olave M, Cascales-Hernandez A, Gago B, Hernandez-Rivas J, Villalon L, Corona M, Roldan-Perez A, Ribes-Amoros J, Gonzalez-Santillana C, Garcia-Sanz R, Navarro D, Serrano-Lopez A, Cedillo A, Soria-Olivas E, Sureda A, Solano C. Annals of Hematology. 2022 Sep;101(9):2053-2067. doi: 10.1007/s00277-022-04906-8. PMID: 35780254

Booster effect after SARS-CoV-2 vaccination in immunocompromised hematology patients with prior COVID-19. Piñana JL, Garcia-Sanz R, Martino R, Garcia-Roa M, Martin-Martin GA, Risco-Gálvez I, Tormo M, Martinez-Barranco P, Marcos-Corrales S, Calabuig M, Conesa V, Teruel A, Ruiz-Pérez S, Solano C, Navarro D, Cedillo Á, Sureda A. Blood Advances. 2022 Jan 8;6(3):848-853. doi: 10.1182/bloodadvances.2021006326. PMID: 34905620

Identifying SARS-CoV-2 ‘memory’ NK cells from COVID-19 convalescent donors for adoptive cell therapy. Herrera L, Martin-Inaraja M, Santos S, Ingles-Ferrandiz M, Azkarate A, Perez-Vaquero MA, Vesga MA, Vicario JL, Soria B, Solano C, De Paz R, Marcos A, Ferreras C, Perez-Martinez A, Eguizabal C. Immunology. 2022 Feb;165(2):234-249. doi: 10.1111/imm.13432. doi: 10.1111/imm.13432. PMID: 34775592

Multi-body-site colonization screening cultures for predicting multi-drug resistant Gram-negative and Gram-positive bacteremia in hematological patients. Torres I, Huntley D, Tormo M, Calabuig M, Hernandez-Boluda J, Terol M, Carretero C, de Michelena P, Perez A, Pinana J, Colomina J, Solano C, Navarro D. BMC Infectious Diseases. 2022 Feb 21;22(1):172. doi: 10.1186/s12879-022-07154-3. PMID: 35189833

Post-transplant cyclophosphamide after HLA identical compared to Haploidentical donor transplant in Acute Myeloid Leukemia: a study on behalf of GETH-TC. Bailen R, Pascual-Cascon M, Guerreiro M, Lopez-Corral L, Chinea A, Bermudez A, Sampol A, Heras I, Garcia-Torres E, Torres M, Roca J, Herruzo B, Sanz J, Fonseca M, Herrera P, Colorado M, Bento L, Lopez-Godino O, Martin-Calvo C, Fernandez-Caldas P, Marcos-Jubilar M, Sanchez-Ortega I, Solano C, Noriega V, Humala K, Oarbeascoa G, Jose Luis Diez-Martin J, Kwon M, Grupo Espanol de Trasplante Hematopoyetico y Terapia Celular (GETH). Transplantation and Cellular Therapy. 2022 Apr;28(4):204.e1-204.e10. doi: 10.1016/j.jtct.2022.01.020. PMID: 35108627

Post-transplant cyclophosphamide and sirolimus based graft-versus-host disease prophylaxis after allogeneic stem cell transplantation for acute myeloid leukemia. Lazzari L, Balaguer-Rosello A, Montoro J, Greco R, Hernani R, Lupo-Stanghellini M, Villalba M, Giglio F, Facal A, Lorentino F, Guerreiro M, Bruno A, Perez A, Xue E, Clerici D, Piemontese S, Pinana J, Sanz M, Solano C, de la Rubia J, Ciceri F, Peccatori J, Sanz J. Bone Marrow Transplantation. 2022 Sep;57(9):1389-1398. doi: 10.1038/s41409-022-01725-3. PMID: 35680995

SARS-CoV-2 vaccine response and rate of breakthrough infection in patients with hematological disorders. Pinana JL, Lopez-Corral L, Martino R, Vazquez L, Perez A, Martin-Martin G, Gago B, Sanz-Linares G, Sanchez-Salinas A, Villalon L, Conesa-Garcia V, Olave MT, Corona M, Marcos-Corrales S, Tormo M, Hernandez-Rivas JA, Montoro J, Rodriguez-Fernandez A, Risco-Galvez I, Rodriguez-Belenguer P, Hernandez-Boluda JC, Garcia-Cadenas I, Ruiz-Garcia M, Munoz-Bellido JL, Solano C, Cedillo A, Sureda A, Navarro D. Journal of Hematology & Oncology. 2022 May 7;15(1):54. doi: 10.1186/s13045-022-01275-7. PMID: 35526045

SARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH-TC). Pinana J, Lopez-Corral L, Martino R, Montoro J, Vazquez L, Perez A, Martin-Martin G, Facal-Malvar A, Ferrer E, Pascual M, Sanz-Linares G, Gago B, Sanchez-Salinas A, Villalon L, Conesa-Garcia V, Olave M, Lopez-Jimenez J, Marcos-Corrales S, Garcia-Blazquez M, Garcia-Gutierrez V, Hernandez-Rivas J, Saus A, Espigado I, Alonso C, Hernani R, Solano C, Ferrer-Lores B, Guerreiro M, Ruiz-Garcia M, Munoz-Bellido J, Navarro D, Cedillo A, Sureda A, Infectious Complications Subcommittee of the Spanish Hematopoietic Stem, Cell Transplantation and Cell Therapy Group (GETH-TC). American Journal of Hematology. 2022 Jan 1;97(1):30-42. doi: 10.1002/ajh.26385. PMID: 34695229

Toxicities following CAR-T therapy for hematological malignancies. Hernani R, Benzaquen A, Solano C. Cancer Treatment Reviews. 2022 Dec;111:102479. doi: 10.1016/j.ctrv.2022.102479. PMID: 36308910

A phase I/II dose-escalation multi-center study to evaluate the safety of infusion of natural killer cells or memory T cells as adoptive therapy in coronavirus pneumonia and/or lymphopenia: RELEASE study protocol. García-García I, Guerra-García P, Ferreras C, Borobia A, Carcas A, Queiruga-Parada J, Vicario J, Mirones I, Solano Vercet C, Eguizabal C, Soria B, Pérez-Martínez A. Trials. 2021 Oct 2;22(1):674. doi: 10.1186/s13063-021-05625-7. PMID: 34600562

Addition of rituximab in reduced intensity conditioning regimens for B-Cell malignancies does not influence transplant outcomes: EBMT registry analyses following allogeneic stem cell transplantation for B-Cell malignancies. Tomaszewska A, Jagasia M, Beohou E, van der Werf S, Blaise D, Kanfer E, Milpied N, Remenyi P, Ciceri F, Bourhis J, Chevallier P, Solano C, Socie G, Bruno B, Rambaldi A, Castagna L, Kroger N, Corradini P, Afanasyev B, Ladetto M, Niederwieser D, Scheid C, Sengeloev H, Kroschinsky F, Yakoub-Agha I, Schoemans H, Koenecke C, Penack O, Peric Z, Greinix H, Duarte R, Basak G. Frontiers in Immunology. 2021 Feb 2;11:613954. doi: 10.3389/fimmu.2020.613954. PMID: 33603743

Allogeneic Hematopoietic Stem Cell Transplant recipients in Spain: Human Leucocyte Antigen characteristics and diversity by high-resolution analysis. Guerreiro M, Planelles D, Aguilar-Gallardo C, Lorenzo J, Montoro J, Sanz J, Balaguer A, Gomez I, Solves P, Perez A, Blanquer M, Espigado I, Solano C, Pinana J, Grupo Espanol de Trasplante Hematopoyetico y Terapia Celular (GETH). HLA. 2021 Mar;97(3):198-213. doi: 10.1111/tan.14179. PMID: 33369244

Amplification of human beta-glucoronidase gene for appraising the accuracy of negative SARS-CoV-2 RT-PCR results in upper respiratory tract specimens. Albert Vicent E, Ferrer Lores B, Torres Fink I, Serrano Alcalá A, Alcaráz Soriana M, Buesa Gomez J, Solano Vercet C, Colomina Rodríguez F, Bueno Ferrando F, Huntley Pascual D, Olea Miguel B, Valdivia Piqueres A, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):48-50. doi: 10.1002/jmv.26112. PMID: 32484950

An investigation of the potential association between gastrointestinal viral and bacterial infection and development of intestinal acute graft versus host disease following allogeneic hematopoietic stem cell transplantation. Bueno F, Albert E, Gimenez E, Pinana J, Perez A, Gomez M, Hernandez-Boluda J, Gonzalez-Barbera E, Montoro J, Buesa J, Guerreiro M, Balaguer-Rosello A, Hernani R, Sanz J, Solano C, Navarro D. Journal of Medical Virology. 2021 Aug;93(8):4773-4779. doi: 10.1002/jmv.26892. PMID: 33605457

Biomarker profile predicts clinical efficacy of extracorporeal photopheresis in steroid-resistant acute and chronic graft-vs-host disease after allogenic hematopoietic stem cell transplant. Amat P, Lopez-Corral L, Goterris R, Perez A, Lopez O, Heras I, Arbona C, Viguria MC, Hernandez-Boluda JC, Martinez-Ruiz F, Martinez A, Solano C. Journal of Clinical Apheresis. 2021 Oct;36(5):697-710. doi: 10.1002/jca.21918. PMID: 34185332

CAR-T therapy in solid transplant recipients with post-transplant lymphoproliferative disease: case report and literature review. Hernani R, Sancho A, Amat P, Hernandez-Boluda J, Perez A, Pinana J, Carretero C, Goterris R, Gomez M, Saus A, Ferrer B, Teruel A, Terol M, Solano C. Current Research in Translational Medicine. 2021 Jul 22;69(4):103304. doi: 10.1016/j.retram.2021.103304. PMID: 34303899

Clinical outcomes of allogeneic hematopoietic stem cell transplant recipients developing Cytomegalovirus DNAemia prior to engraftment. Solano C, Vazquez L, Gimenez E, de la Camara R, Albert E, Rovira M, Espigado I, Calvo C, Lopez-Jimenez J, Suarez-Lledo M, Chinea A, Esquirol A, Perez A, Bermudez A, Saldana R, Heras I, Gonzalez-Huerta A, Torrado T, Batlle M, Jimenez S, Vallejo C, Barba P, Cuesta M, Pinana J, Navarro D, Spanish Group of Hematopoietic Transplantation and Cell Therapy (GETH). Bone Marrow Transplantation. 2021 Jun;56(6):1281-1290. doi: 10.1038/s41409-020-01157-x. PMID: 33319853

Cytomegalovirus DNAemia and risk of mortality in allogeneic hematopoietic stem cell transplantation: Analysis from the Spanish Hematopoietic Transplantation and Cell Therapy Group. Solano Vercet C, Vazquez L, Gimenez Quiles E, De La Camara R, Albert Vicent E, Rovira M, Espigado I, Calvo C, Lopez-Jimenez J, Suarez-Lledo M, Chinea A, Esquirol A, Perez Martinez A, Bermudez A, Saldana R, Heras I, Gonzalez-Huerta A, Torrado T, Bautista G, Batlle M, Jimenez S, Vallejo C, Barba P, Cuesta M, Pinana J, Navarro Ortega D. American Journal of Transplantation. 2021 Jan;21(1):258-271. doi: 10.1111/ajt.16147. PMID: 32812351

Cytomegalovirus-specific T-cell immunity and DNAemia in patients with chronic lymphocytic leukaemia undergoing treatment with ibrutinib. De la Asuncion C, Terol M, Saus A, Olea B, Gimenez E, Albert E, Lopez-Jimenez J, Andreu R, Garcia D, Fox L, Remigia M, Amat P, Solano C, Navarro D. British Journal of Haematology. 2021 Nov;195(4):637-641. doi: 10.1111/bjh.17732. PMID: 34402042

Diversity and dynamic changes of Anelloviruses in plasma following Allogeneic Hematopoietic Stem Cell Transplantation. Gimenez Quiles E, Monzo Cataluña C, Albert Vicent E, Fuentes Trillo A, Seda García E, Pinana J, Hernandez Boluda J, Solano Vercet C, Chaves Martínez F, Navarro Ortega D. Journal of Medical Virology. 2021 Aug;93(8):5167-5172. doi: 10.1002/jmv.26661. PMID: 33174620

Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: a systematic review of comparative studies for health outcomes, experience of care and costs. Gonzalez M, Urizar E, Urtaran-Laresgoiti M, Nuno-Solinis R, Lazaro-Perez E, Vazquez L, Pascual-Cascon M, Solano C, Kwon M, Gallego C, Fernandez-Aviles F. PLoS One. 2021 Aug 12;16(8):e0254135. doi: 10.1371/journal.pone.0254135. PMID: 34383780

Myelodysplastic syndromes with 20q deletion: incidence, prognostic value and impact on response to azacitidine of ASXL1 chromosomal deletion and genetic mutations. Martin I, Villamon E, Abellan R, Calasanz M, Irigoyen A, Sanz G, Such E, Mora E, Gutierrez M, Collado R, Garcia-Serra R, Vara M, Blanco M, Oiartzabal I, Alvarez S, Bernal T, Granada I, Xicoy B, Jerez A, Calabuig M, Diez R, Gil A, Diez-Campelo M, Solano C, Tormo M, Spanish Grp Myelodysplastic Syn. British Journal of Haematology. 2021 Aug;194(4):708-717. doi: 10.1111/bjh.17675. PMID: 34296432

Real-world evidence of tisagenlecleucel for the treatment of relapsed or refractory large B-cell lymphoma. Cancer medicine. Iacoboni G, Villacampa G, Martinez-Cibrian N, Bailen R, Lopez Corral L, Sanchez J, Guerreiro M, Caballero A, Mussetti A, Sancho J, Hernani Morales R, Abrisqueta P, Solano Vercet C, Sureda A, Briones J, Martin Garcia-Sancho A, Kwon M, Reguera-Ortega J, Barba P, GETH G. 2021 May;10(10):3214-3223. doi: 10.1002/cam4.3881. PMID: 33932100

SARS-CoV-2-reactive interferon-gamma-producing CD8+ T cells in patients hospitalized with Coronavirus Disease 2019. Gimenez Quiles E, Albert Vicent E, Torres Fink I, Remigia Pellicer M, Alcaráz Soriana M, Galindo Puerto M, Blasco Cortes M, Solano Vercet C, Forner Giner M, Redón Mas J, Signes-Costa Miñana J, Navarro Ortega D. Journal of Medical Virology. 2021 Jan;93(1):375-382. doi: 10.1002/jmv.26213. PMID: 32579268

SARS-CoV-2-specific memory t lymphocytes from COVID-19 convalescent donors: identification, biobanking, and large-scale production for adoptive cell therapy. Ferreras C, Pascual-Miguel B, Mestre-Duran C, Navarro-Zapata A, Clares-Villa L, Martin-Cortazar C, De Paz R, Marcos A, Vicario J, Balas A, Garcia-Sanchez F, Eguizabal C, Solano C, Mora-Rillo M, Soria B, Perez-Martinez A. Frontiers in Cell and Developmental Biology. 2021 Feb 25;9:620730. doi: 10.3389/fcell.2021.620730. PMID: 33718360

Seasonal human coronaviruses respiratory tract infection in recipients of allogeneic hematopoietic stem cell transplantation. Pinana J, Xhaard A, Tridello G, Passweg J, Kozijn A, Polverelli N, Heras I, Perez A, Sanz J, Berghuis D, Vazquez L, Suarez-Lledo M, Itala-Remes M, Ozcelik T, Iturrate Basaran I, Karakukcu M, Al Zahrani M, Choi G, Cuesta Casas M, Batlle Massana M, Viviana A, Blijlevens N, Ganser A, Kuskonmaz B, Labussiere-Wallet H, Shaw P, Arzu Yegin Z, Gonzalez-Vicent M, Rocha V, Ferster A, Knelange N, Navarro D, Mikulska M, de la Camara R, Styczynski J, Infectious Diseases Working Party of the European Society for Blood and, Marrow Transplantation and Infectious Complications Subcommittee of the, Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group, (GETH). The Journal of Infectious Diseases. 2021 May 20;223(9):1564-1575. doi: 10.1093/infdis/jiaa553. PMID: 32860509

Use of letermovir in off-label indications: Infectious Diseases Working Party of European Society of Blood and Marrow Transplantation retrospective study. Styczynski J, Tridello G, Xhaard A, Medinger M, Mielke S, Taskinen M, Blijlevens N, Rodriguez M, Solano C, Nikolousis E, Biffi A, Groll A, Junghanss C, Tsirigotis P, Lioure B, Sramek J, Holler E, Galaverna F, Fagioli F, Knelange N, Wendel L, Gil L, de la Camara R, Mikulska M, Ljungman P. Bone Marrow Transplantation. 2021 May;56(5):1171-1179. doi: 10.1038/s41409-020-01166-w. PMID: 33288863

Projects
Reference: PI21/01628
Title: Inmunobiología de células NK expandidas con criterios GMP de donantes seleccionados de banco de linfocitos para inmunoterapia adoptiva después de TPH alogénico o trasplante de órgano sólido
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Carlos Solano Vercet
Duration: 2022 – 2024
Total budget: 102.850 €
Reference: BIO21/COV/030
Title: Estudio de la inmunidad y Creación de un Banco Nacional de Terapia Celular Adoptiva de donantes de linfocitos que han superado COVID-19. Ensayo clínico Fase I multicéntrico para evaluar la seguridad de la infusión de células natural killer como terapia adoptiva en casos pacientes con neumonía y/o linfopenia debido al coronavirus SARS-CoV-2 (RELEASE)
Funding body: Fundación Vasca de Innovación e investigación Sanitarias (BIOEFF)
Principal Investigator: Cristina Eguizabal
Duration: 2021 – 2022
Total budget: 99.935 €
Reference: GV/2020/188
Title: Anellovirus y Pegivirus un posible marcador del estado neto de inmunosupresión: evaluación en el trasplante alogénico de progenitores hematopoyéticos
Funding body: Conselleria de Educación, Cultura y Deporte
Principal Investigator: Estela Giménez Quiles
Duration: 2020 – 2021
Total budget: 16.000 €
Reference: AP178182020
Title: Estudio de la inmunidad y Creación de un Banco Nacional de Terapia Celular Adoptiva de donantes de linfocitos que han superado COVID-19. Ensayo clínico Fase I multicéntrico para evaluar la seguridad de la infusión de células natural killer como terapia adoptiva en casos pacientes con neumonía y/o linfopenia debido al coronavirus SARS-CoV-2 (RELEASE)
Funding body: Fundación Mutua Madrileña
Principal Investigator: Cristina Eguizabal
Duration: 2020 – 2021
Total budget: 100.000 €
Reference: PI18/01473
Title: Inmunología de la infusión de linfocitos del donante con depleción ex vivo de linfocitos t cd45ra+ en pacientes con alto riesgo de infección viral tras TPH alogénico
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Carlos Solano Vercet
Duration: 2019 – 2023
Total budget: 123.420 €
Reference: PI15/01396
Title: Inmunobiología de la aloreactividad NK en el trasplante de progenitores hematopoyéticos haploidenticos asociado al uso de ciclofosfamida post-trasplante
Funding body: Instituto de Salud Carlos III – Cofinanciado FEDER
Principal Investigator: Carlos Solano Vercet
Duration: 2016 – 2019
Total budget: 116.765 €
+ Info
Title: Impacto de la alorreactividad NK en el trasplante haploidéntico de progenitores hematopoyéticos asociado al uso de la ciclofosfamida postrasplante
Doctoral candidate: Luis Hidalgo, Mª Mar
Director(s): Solano Vercet, Carlos; Piñana Sánchez, Jose Luis; Planelles Silvestre, Dolores
Date of the defense: 21/12/2022
University: Universitat de València

Title: Significado pronóstico de la expresión del factor de crecimiento endotelial vascular (VEGF) y de genes implicados en las vías de señalización del VEGF en pacientes con leucemia aguda mieloblástica
Doctoral candidate: Calabuig Muñoz, Marisa
Director(s): Tormo Díaz, Mar; Solano Vercet, Carlos
Date of the defense: 04/05/2022
University: Universitat de València

Title: Estudio de la enfermedad residual mínima en pacientes con mieloma múltiple en muy buena respuesta parcial o completa convencional mediante citometría de flujo de alta sensibilidad y la medición de cadenas mediante la técnica Hevylite
Doctoral candidate: Remigia Pellicer, María José
Director(s): De la Rubia Comos, Javier; Sempere Talens, Amparo; Solano Vercet, Carlos
Date of the defense: 04/06/2021
University: Universitat de València